Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 10/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.43 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1122737 | 0.88 | PKM (0.60) | PARP10TSHRKDM4EL3MBTL1GAA | |
| SCHEMBL1123053 | 0.86 | MAPT (0.63) | TSHRKDM4EL3MBTL1GAASMN1; SMN2 | |
| SCHEMBL1123321 | 0.77 | KMT2A (0.57) | TSHRKDM4EL3MBTL1SMN1; SMN2PKM | |
| SCHEMBL1123404 | 0.76 | GPR132 (0.56) | TSHRGAARAB9A | |
| SCHEMBL1122629 | 0.75 | CYSLTR1 (0.57) | TSHRKDM4EL3MBTL1GAASMN1; SMN2 | |
| SCHEMBL1122623 | 0.74 | GAA (0.64) | TSHRGAAALDH1A1RAB9AGLA | |
| SCHEMBL5720727 | 0.74 | TSHR (0.70) | TSHRKDM4EL3MBTL1GAASMN1; SMN2 | |
| SCHEMBL1123269 | 0.73 | L3MBTL1 (0.50) | TSHRL3MBTL1ALDH1A1MAPTRAB9A | |
| SCHEMBL3011807 | 0.72 | PARP10 (0.71) | PARP10L3MBTL1PKMALDH1A1MAPT | |
| SCHEMBL5720823 | 0.72 | TSHR (0.51) | TSHRKDM4EL3MBTL1GAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060160894-A1 | Benzamides as ppar modulators | LABORATORIOS S.A.L.V.A.T.,S.A. (ES) | 2006-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060160894-A1 | Benzamides as ppar modulators | PPARD, PPARA, PPARG | PARP10 398/4885TSHR 240/4885KDM4E 2065/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.