Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.60 |
| ▸ | NPC1 | O15118 | 4/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.60 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.60 |
| ▸ | CASP3 | P42574 | 1/20 | 0.60 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | BRD4 | O60885 | 1/20 | 0.54 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.54 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.53 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.52 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1123501 | 0.90 | L3MBTL1 (0.63) | RAB9ANPC1SMN1; SMN2SENP7CASP3 | |
| SCHEMBL1122992 | 0.88 | SMN1; SMN2 (0.61) | RAB9ANPC1SMN1; SMN2SENP7CASP3 | |
| SCHEMBL1123139 | 0.86 | NPC1 (0.74) | RAB9ANPC1SMN1; SMN2SENP7CASP3 | |
| SCHEMBL1123414 | 0.86 | SMN1; SMN2 (0.61) | RAB9ANPC1SMN1; SMN2SENP7CASP3 | |
| SCHEMBL1123323 | 0.84 | PLK1 (0.64) | RAB9ANPC1SMN1; SMN2SENP7CASP3 | |
| SCHEMBL1123220 | 0.83 | NPC1 (0.60) | RAB9ANPC1SMN1; SMN2SENP7CASP3 | |
| SCHEMBL1123204 | 0.83 | SENP7 (0.65) | RAB9ANPC1SMN1; SMN2SENP7CASP3 | |
| SCHEMBL1123418 | 0.81 | NR1H4 (0.65) | RAB9ANPC1SMN1; SMN2SENP7CASP3 | |
| SCHEMBL38660185 | 0.81 | BRD4 (0.70) | RAB9ANPC1SMN1; SMN2SENP7CASP3 | |
| SCHEMBL11549645 | 0.81 | BRD4 (0.70) | RAB9ANPC1SMN1; SMN2SENP7CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1644321-B1 | NEW BENZAMIDES AS PPATY MODULATORS | S A L V A T LAB SA (ES) | 2011-02-09 | — | — | EP | claimed |