Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.53 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | CTSS | P25774 | 5/20 | 0.45 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.45 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.45 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.44 |
| ▸ | PLG | P00747 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1122538 | 0.94 | BDKRB2 (0.50) | TAS1R3TAS1R1GAARAB9ACTSS | |
| SCHEMBL1123135 | 0.91 | GPR132 (0.54) | RAB9ACTSSGPR132BDKRB2CTSL | |
| SCHEMBL1122690 | 0.85 | GPR132 (0.53) | CTSSGPR132BDKRB2SLC6A5PLG | |
| SCHEMBL1122814 | 0.85 | GPR132 (0.53) | CTSSGPR132BDKRB2SLC6A5PLG | |
| SCHEMBL1123575 | 0.84 | GPR132 (0.58) | GAARAB9ACTSSGPR132CTSL | |
| SCHEMBL1123574 | 0.84 | GPR132 (0.58) | GAARAB9ACTSSGPR132CTSL | |
| SCHEMBL1123156 | 0.83 | GPR132 (0.58) | RAB9ACTSSGPR132BDKRB2CTSL | |
| SCHEMBL1123253 | 0.82 | GPR132 (0.65) | GAARAB9ACTSSGPR132CTSL | |
| SCHEMBL1123151 | 0.82 | MAOB (0.52) | GAARAB9ACTSSGPR132PRSS1 | |
| SCHEMBL5720786 | 0.81 | BDKRB2 (0.52) | BDKRB2SLC6A5ALDH1A1MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1644321-B1 | NEW BENZAMIDES AS PPATY MODULATORS | S A L V A T LAB SA (ES) | 2011-02-09 | — | — | EP | disclosed |