Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR132 | Q9UNW8 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | CTSS | P25774 | 9/20 | 0.51 |
| ▸ | YAP1 | P46937 | 3/20 | 0.49 |
| ▸ | CTSL | P07711 | 5/20 | 0.48 |
| ▸ | CTSB | P07858 | 2/20 | 0.48 |
| ▸ | CTSK | P43235 | 2/20 | 0.48 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.46 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.46 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.46 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.46 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1123574 | 1.00 | GPR132 (0.58) | GPR132GAARAB9ACTSSYAP1 | |
| SCHEMBL1122740 | 0.94 | GPR132 (0.66) | GPR132CTSSYAP1CTSLCTSB | |
| SCHEMBL1123253 | 0.93 | GPR132 (0.65) | GPR132GAARAB9ACTSSYAP1 | |
| SCHEMBL1123390 | 0.92 | GPR132 (0.68) | GPR132CTSSCTSLCTSBCTSK | |
| SCHEMBL1123151 | 0.89 | MAOB (0.52) | GPR132GAARAB9ACTSSYAP1 | |
| SCHEMBL1123392 | 0.85 | GPR132 (0.78) | GPR132CTSSCTSLCTSBCTSK | |
| SCHEMBL1123215 | 0.84 | TAS1R3 (0.53) | GPR132GAARAB9ACTSSCTSL | |
| SCHEMBL1123119 | 0.84 | GPR132 (0.77) | GPR132CTSSCTSLPTPN1 | |
| SCHEMBL1123382 | 0.83 | GAA (0.71) | GPR132GAARAB9AYAP1PTPN1 | |
| SCHEMBL1122538 | 0.82 | BDKRB2 (0.50) | GPR132GAARAB9ACTSSYAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1644321-B1 | NEW BENZAMIDES AS PPATY MODULATORS | S A L V A T LAB SA (ES) | 2011-02-09 | — | — | EP | disclosed |