Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.52 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.49 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.49 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | KDM1A | O60341 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1122784 | 0.91 | GPR132 (0.62) | MAOBGPR132RAB9APARP15PARP14 | |
| SCHEMBL1123574 | 0.89 | GPR132 (0.58) | GPR132RAB9AGAACTSSMRGPRX4 | |
| SCHEMBL1123575 | 0.89 | GPR132 (0.58) | GPR132RAB9AGAACTSSMRGPRX4 | |
| SCHEMBL1123253 | 0.83 | GPR132 (0.65) | GPR132RAB9AGAACTSSCTSL | |
| SCHEMBL1122740 | 0.82 | GPR132 (0.66) | MAOBGPR132CTSSCTSLCTSK | |
| SCHEMBL1123215 | 0.82 | TAS1R3 (0.53) | GPR132RAB9AGAAMAPTHTT | |
| SCHEMBL1123063 | 0.81 | GAA (0.67) | MAOBGPR132RAB9AGAAPARP15 | |
| SCHEMBL27638044 | 0.81 | GAA (0.67) | MAOBGPR132RAB9AGAAPARP15 | |
| SCHEMBL1122538 | 0.80 | BDKRB2 (0.50) | GPR132RAB9AGAACTSSCTSL | |
| SCHEMBL1123390 | 0.80 | GPR132 (0.68) | GPR132CTSSCTSLCTSKCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1644321-B1 | NEW BENZAMIDES AS PPATY MODULATORS | S A L V A T LAB SA (ES) | 2011-02-09 | — | — | EP | disclosed |