Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PCTP | Q9UKL6 | 2/20 | 0.59 |
| ▸ | NAMPT | P43490 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | SMO | Q99835 | 2/20 | 0.50 |
| ▸ | STARD10 | Q9Y365 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | MITF | O75030 | 1/20 | 0.48 |
| ▸ | UBE2N | P61088 | 1/20 | 0.48 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.48 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.48 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11243565 | 0.85 | GCGR (0.52) | PCTPTDP1CA1CA2CA9 | |
| SCHEMBL11138392 | 0.80 | PCTP (0.60) | PCTPKMT2ATDP1CA1CA2 | |
| SCHEMBL11396424 | 0.79 | TDP1 (0.59) | PCTPKMT2ATDP1SMOPOLB | |
| SCHEMBL11139993 | 0.78 | TDP1 (0.65) | PCTPNAMPTKMT2ATDP1CA1 | |
| SCHEMBL10704913 | 0.78 | TDP1 (0.64) | PCTPKMT2ATDP1SMOPOLB | |
| Chlorbenzuron SCHEMBL5177776 | 0.78 | GCGR (0.68) | PCTPKMT2ATDP1SMOPOLB | |
| SCHEMBL19377260 | 0.77 | PCTP (0.46) | PCTPNAMPTKMT2ACA1CA2 | |
| SCHEMBL11250867 | 0.77 | TDP1 (0.63) | KMT2ATDP1CA1CA2CA9 | |
| SCHEMBL11243517 | 0.77 | PCTP (0.57) | PCTPKMT2ATDP1CA1CA2 | |
| SCHEMBL10618489 | 0.76 | TSHR (0.63) | NAMPTKMT2ACA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4350706-A | MITICIDES, LARVICIDES | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1982-09-21 | — | — | US | disclosed |