Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.65 |
| ▸ | PCTP | Q9UKL6 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | CA9 | Q16790 | 1/20 | 0.55 |
| ▸ | RORC | P51449 | 1/20 | 0.53 |
| ▸ | PLCG2 | P16885 | 1/20 | 0.51 |
| ▸ | STARD10 | Q9Y365 | 1/20 | 0.48 |
| ▸ | GCGR | P47871 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | KIF11 | P52732 | 1/20 | 0.48 |
| ▸ | SMO | Q99835 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11138392 | 0.82 | PCTP (0.60) | TDP1PCTPKMT2ACA1CA2 | |
| Chlotrifmeuron SCHEMBL10868747 | 0.82 | TDP1 (0.70) | TDP1PCTPKMT2ARORCPLCG2 | |
| SCHEMBL11138747 | 0.80 | TDP1 (0.67) | TDP1PCTPKMT2ARORCPLCG2 | |
| Chlorbenzuron SCHEMBL5177776 | 0.80 | GCGR (0.68) | TDP1PCTPKMT2ARORCPLCG2 | |
| SCHEMBL11395735 | 0.80 | RORC (0.82) | TDP1PCTPKMT2ARORCPLCG2 | |
| Triflumuron SCHEMBL9490691 | 0.79 | TDP1 (1.00) | TDP1PCTPKMT2ARORCPLCG2 | |
| Triflumuron SCHEMBL29832813 | 0.79 | TDP1 (1.00) | TDP1PCTPKMT2ARORCPLCG2 | |
| Triflumuron SCHEMBL23700 | 0.79 | TDP1 (1.00) | TDP1PCTPKMT2ARORCPLCG2 | |
| SCHEMBL11232803 | 0.78 | PCTP (0.59) | TDP1PCTPKMT2ACA1CA2 | |
| SCHEMBL9083215 | 0.78 | KIF11 (0.68) | KMT2ACA1CA2CA9KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4399152-A | Substituted benzoyl ureas as insecticides | DUPHAR INTERNATIONAL B.V. (NL) | 1983-08-16 | — | — | US | disclosed |