Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | GPR139 | Q6DWJ6 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | METAP2 | P50579 | 2/20 | 0.42 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
| ▸ | METAP1 | P53582 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | ACACB | O00763 | 1/20 | 0.42 |
| ▸ | USP36 | Q9P275 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11236872 | 0.89 | SMN1; SMN2 (0.47) | LMNANPC1RAB9AGPR139SMN1; SMN2 | |
| SCHEMBL11573236 | 0.84 | L3MBTL1 (0.44) | LMNANPC1RAB9AMEN1KMT2A | |
| SCHEMBL11246295 | 0.83 | CHRM1 (0.49) | NPC1RAB9AL3MBTL1SMN1; SMN2HPGD | |
| SCHEMBL11218340 | 0.80 | LMNA (0.49) | LMNARAB9AMEN1KMT2AL3MBTL1 | |
| SCHEMBL11241426 | 0.77 | SMN1; SMN2 (0.47) | NPC1RAB9ASMN1; SMN2HPGDACACB | |
| SCHEMBL11233259 | 0.77 | SMN1; SMN2 (0.51) | LMNANPC1RAB9AGPR139SMN1; SMN2 | |
| SCHEMBL2159283 | 0.72 | HPGD (0.61) | LMNANPC1RAB9AGPR139MEN1 | |
| SCHEMBL11353964 | 0.71 | TSHR (0.51) | LMNAMEN1KMT2AL3MBTL1 | |
| SCHEMBL11367238 | 0.71 | TSHR (0.51) | LMNANPC1RAB9AMEN1KMT2A | |
| SCHEMBL11382273 | 0.71 | NPC1 (0.52) | NPC1RAB9ASMN1; SMN2HPGDCHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-57171947-A | — | — | None | — | — | JP | disclosed |
| JP-S57171947-A | NOVEL OXYACETIC ACID DERIVATIVE, ITS PREPARATION, AND BLOOD LIPID LEVEL DEPRESSANT CONTAINING SAID DERIVATIVE AS ACTIVE COMPONENT | KAKEN PHARMACEUT CO LTD | 1982-10-22 | — | — | JP | disclosed |