Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.30 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31756330 | 0.81 | CA12 (0.33) | — | |
| SCHEMBL8193841 | 0.79 | CHRM2 (0.30) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL6840728 | 0.68 | CFD (0.38) | — | |
| SCHEMBL2480841 | 0.65 | CHRNB2 (0.32) | — | |
| SCHEMBL1016586 | 0.62 | — | — | |
| SCHEMBL11063185 | 0.61 | — | — | |
| SCHEMBL7778455 | 0.60 | NQO2 (0.34) | — | |
| SCHEMBL3894497 | 0.59 | CYP2A6 (0.42) | — | |
| SCHEMBL2880364 | 0.59 | — | — | |
| SCHEMBL2005620 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4331802-A | Organometallic reagents and their use in the synthesis of cardenolides and isocardenolides | ADVANCE BIOFACTURES CORPORATION (US) | 1982-05-25 | — | — | US | disclosed |