Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | LDHA | P00338 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL667750 | 0.97 | CYP2A6 (0.40) | CYP2A6MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL10528634 | 0.93 | MAPK1 (0.42) | CYP2A6MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL4763549 | 0.86 | CA1 (0.39) | ALDH1A1MEN1KMT2AMAPK1CA1 | |
| SCHEMBL7688488 | 0.84 | LMNA (0.65) | MAPTMEN1KMT2ARAB9ANPSR1 | |
| SCHEMBL7688132 | 0.84 | MAPT (0.42) | MAPTMEN1KMT2ARAB9ANPSR1 | |
| SCHEMBL10951164 | 0.80 | CYP2A6 (0.38) | CYP2A6MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL8171076 | 0.80 | NCEH1 (0.47) | CYP2A6MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL614621 | 0.78 | PREP (0.47) | CYP2A6MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL17881929 | 0.78 | ESR2 (0.39) | MAPTALDH1A1KMT2ARAB9AMAPK1 | |
| SCHEMBL9714337 | 0.78 | ESR2 (0.39) | MAPTALDH1A1KMT2ARAB9AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111617646-B | Preparation method of chiral conjugated microporous polymer/silicon dioxide composite membrane | 齐齐哈尔大学 | 2022-03-04 | — | — | CN | claimed |
| CN-111617646-A | Preparation method of chiral conjugated microporous polymer/silicon dioxide composite membrane | 齐齐哈尔大学 | 2020-09-04 | — | — | CN | claimed |
| US-10385093-B2 | Estrogen receptor imaging agents | NORTHEASTERN UNIVERSITY (US) | 2019-08-20 | — | — | US | claimed |
| US-20150344518-A1 | ESTROGEN RECEPTOR IMAGING AGENTS | UNITED STATES DEPARTMENT OF ENERGY | 2015-12-03 | — | — | US | claimed |
| WO-2014093378-A1 | ESTROGEN RECEPTOR IMAGING AGENTS | NORTHEASTERN UNIVERSITY (US) | 2014-06-19 | — | — | WO | claimed |
| US-11912731-B2 | Use of silylated formiates as hydrosilane equivalents | COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) | 2024-02-27 | — | — | US | disclosed |
| CN-114181244-A | Preparation method of alkyl siloxy halogenated benzene | 宁夏中星显示材料有限公司 | 2022-03-15 | — | — | CN | disclosed |
| CN-111617646-B | Preparation method of chiral conjugated microporous polymer/silicon dioxide composite membrane | 齐齐哈尔大学 | 2022-03-04 | — | — | CN | disclosed |
| CN-109912455-B | Method for preparing 4-hydroxy-4' -cyanobiphenyl | 宁夏中星显示材料有限公司 | 2022-03-01 | — | — | CN | disclosed |
| CN-111617646-A | Preparation method of chiral conjugated microporous polymer/silicon dioxide composite membrane | 齐齐哈尔大学 | 2020-09-04 | — | — | CN | disclosed |
| US-10385093-B2 | Estrogen receptor imaging agents | NORTHEASTERN UNIVERSITY (US) | 2019-08-20 | — | — | US | disclosed |
| US-20150344518-A1 | ESTROGEN RECEPTOR IMAGING AGENTS | UNITED STATES DEPARTMENT OF ENERGY | 2015-12-03 | — | — | US | disclosed |
| US-5149696-A | Antiestrogens | ROUSSEL UCLAF (FR) | 1992-09-22 | — | — | US | disclosed |
| EP-0471612-A2 | New steroids having an amide substituted group in the 11-beta position, their preparation, their use as medicines and pharmaceutical composition thereof | ROUSSEL UCLAF (FR) | 1992-02-19 | — | — | EP | disclosed |
| WO-1991009855-A1 | PHARMACEUTICALLY ACTIVE NORMONYL COMPOUNDS | BEECHAM GROUP PLC (GB) | 1991-07-11 | — | — | WO | disclosed |
| EP-0384842-A1 | 19-Nor steroids substituted at position 11-beta by a hydrocarbon chain containing an amide or carbamate group, their preparation, intermediates, their use as medicaments and pharmaceutical compositions containing them | ROUSSEL-UCLAF (FR) | 1990-08-29 | — | — | EP | disclosed |
| US-4500628-A | IRRADIATING FILM CONSISTING OF POLYMER AND ORGANOSILICON MONOMER | AT&T BELL LABORATORIES (US) | 1985-02-19 | — | — | US | disclosed |
| US-4396704-A | Solid state devices produced by organometallic plasma developed resists | BELL TELEPHONE LABORATORIES, INCORPORATED (US) | 1983-08-02 | — | — | US | disclosed |
| US-3992536-A | SEDATIVES AND MUSCLE RELAXANTS | BOEHRINGER INGELHEIM GMBH (DT) | 1976-11-16 | — | — | US | disclosed |
| US-3931185-A | SEDATIVES, MUSCLE RELAXANT | BOEHRINGER INGELHEIM GMBH (DT) | 1976-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11912731-B2 | Use of silylated formiates as hydrosilane equivalents | PFAS, EPM2A, CYP2F1 | CYP2A6 483/4885MAPT 666/4885ALDH1A1 112/4885 |
| US-10385093-B2 | Estrogen receptor imaging agents | ESR1, GPER1, ESR2 | CYP2A6 1208/4885MAPT 1851/4885ALDH1A1 1661/4885 |
| US-20150344518-A1 | ESTROGEN RECEPTOR IMAGING AGENTS | ESR1, GPER1, ESR2 | CYP2A6 1208/4885MAPT 1851/4885ALDH1A1 1661/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.