Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB4 | P30926 | 5/20 | 0.46 |
| ▸ | CHRNA3 | P32297 | 5/20 | 0.46 |
| ▸ | CHRNB2 | P17787 | 4/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.46 |
| ▸ | CHRNA1 | P02708 | 4/20 | 0.46 |
| ▸ | CHRNA2 | Q15822 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.46 |
| ▸ | CHRNG | P07510 | 2/20 | 0.46 |
| ▸ | CHRNB1 | P11230 | 2/20 | 0.46 |
| ▸ | CHRND | Q07001 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.46 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.46 |
| ▸ | HTR3B | O95264 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30866547 | 1.00 | CHRNB4 (0.46) | CHRNB4CHRNA3CHRNB2CHRNA4CHRNA1 | |
| SCHEMBL27200145 | 1.00 | CHRNB4 (0.46) | CHRNB4CHRNA3CHRNB2CHRNA4CHRNA1 | |
| SCHEMBL31019623 | 1.00 | CHRNB4 (0.46) | CHRNB4CHRNA3CHRNB2CHRNA4CHRNA1 | |
| Acetic Acid SCHEMBL27199898 | 0.91 | KDM4E (0.43) | CHRNB4CHRNA3CHRNB2CHRNA4CHRNA1 | |
| Lactic Acid SCHEMBL27199854 | 0.87 | BLM (0.48) | CHRNB4CHRNA3CHRNB2CHRNA4CHRNA1 | |
| L-Lactic Acid SCHEMBL27199862 | 0.87 | BLM (0.48) | CHRNB4CHRNA3CHRNB2CHRNA4CHRNA1 | |
| Cadaverine Tartrate SCHEMBL30866583 | 0.87 | BLM (0.57) | CHRNB4CHRNA3CHRNB2CHRNA4CHRNA1 | |
| Benzoic Acid SCHEMBL27199910 | 0.84 | BLM (0.44) | CHRNB4CHRNA3CHRNB2CHRNA4CHRNA1 | |
| SCHEMBL14389477 | 0.84 | ALDH1A1 (0.44) | CHRNB4CHRNA3CHRNB2CHRNA4CHRNA1 | |
| Levulinic Acid SCHEMBL27199853 | 0.83 | KDM4E (0.38) | CHRNB4CHRNA3CHRNB2CHRNA4CHRNA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11964958-B1 | Vaporizable alkaloid compositions and methods of use thereof | Ready Mix Naturals, LLC (US) | 2024-04-23 | — | — | US | claimed |
| US-11964958-B1 | Vaporizable alkaloid compositions and methods of use thereof | Ready Mix Naturals, LLC (US) | 2024-04-23 | — | — | US | disclosed |
| US-4321387-A | Process for the preparation of optically active nicotine analogs | PHILIP MORRIS, INCORPORATED (US) | 1982-03-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11964958-B1 | Vaporizable alkaloid compositions and methods of use thereof | SRM, SCLY, SMOX | CHRNB4 55/4885CHRNA3 116/4885CHRNB2 98/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.