Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | GAA | P10253 | 4/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | IGF1R | P08069 | 1/20 | 0.48 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11085799 | 0.86 | CDK1 (0.53) | MAPTKDM4EGAANPSR1TDP1 | |
| SCHEMBL11233780 | 0.85 | MAPT (0.62) | MAPTKDM4EGAANPSR1ALDH1A1 | |
| SCHEMBL4555022 | 0.81 | MAPT (0.67) | MAPTKDM4EGAANPSR1TDP1 | |
| SCHEMBL11251035 | 0.81 | MAOA (0.59) | MAPTKDM4EGAANPSR1TDP1 | |
| SCHEMBL8956455 | 0.77 | MAPT (0.75) | MAPTKDM4EGAANPSR1MAOB | |
| SCHEMBL5445907 | 0.77 | MAPT (0.75) | MAPTKDM4EGAANPSR1MAOB | |
| SCHEMBL4555515 | 0.75 | LMNA (0.68) | MAPTKDM4EGAANPSR1TDP1 | |
| SCHEMBL24513146 | 0.75 | ORAI1 (0.59) | MAPTKDM4ETDP1SMN1; SMN2LMNA | |
| SCHEMBL3534972 | 0.73 | MAPT (0.58) | MAPTKDM4EGAANPSR1TDP1 | |
| SCHEMBL18025324 | 0.73 | MAPT (0.56) | MAPTKDM4EGAANPSR1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4331669-A | Fungicidal pyridyl arylureas, compositions containing them and method of controlling fungi and bacteria | DOW CHEMICAL COMPANY LIMITED, ENGLAND (GB) | 1982-05-25 | — | — | US | claimed |