Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR34 | Q9UPC5 | 6/20 | 0.50 |
| ▸ | GPR132 | Q9UNW8 | 3/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.46 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.46 |
| ▸ | CDC25B | P30305 | 1/20 | 0.46 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.45 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1123310 | 0.79 | PTPN1 (0.61) | GPR34GPR132PTPN1ITGB3ITGA2B | |
| SCHEMBL1123267 | 0.78 | GPR132 (0.62) | GPR34GPR132PTPN1ITGB3ITGA2B | |
| SCHEMBL1123396 | 0.77 | GPR34 (0.58) | GPR34GPR132PTPN1PTPN2CDC25B | |
| SCHEMBL1123232 | 0.77 | GPR132 (0.77) | GPR34GPR132PTPN1ITGB3ITGA2B | |
| SCHEMBL27658914 | 0.77 | GPR132 (0.77) | GPR34GPR132PTPN1ITGB3ITGA2B | |
| SCHEMBL1123033 | 0.77 | GPR132 (0.77) | GPR34GPR132PTPN1ITGB3ITGA2B | |
| SCHEMBL1123299 | 0.77 | GPR132 (0.77) | GPR34GPR132PTPN1ITGB3ITGA2B | |
| SCHEMBL1122788 | 0.76 | GPR132 (0.62) | GPR34GPR132PTPN1ITGB3ITGA2B | |
| SCHEMBL1122851 | 0.76 | PTPN1 (0.74) | GPR34GPR132PTPN1PTPN2CDC25B | |
| SCHEMBL1122757 | 0.75 | GPR132 (0.78) | GPR34GPR132PTPN1ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1644321-B1 | NEW BENZAMIDES AS PPATY MODULATORS | S A L V A T LAB SA (ES) | 2011-02-09 | — | — | EP | disclosed |