Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 3/20 | 0.59 |
| ▸ | NR1H4 | Q96RI1 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1122980 | 0.91 | NR1H4 (0.56) | SMPD1NR1H4MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL5720726 | 0.90 | RAB9A (0.60) | NR1H4MEN1KMT2ANR4A2SMN1; SMN2 | |
| SCHEMBL5936672 | 0.85 | SMPD1 (0.60) | SMPD1NR1H4MEN1KMT2ANR4A2 | |
| SCHEMBL5936675 | 0.80 | NR1H4 (0.67) | SMPD1NR1H4MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL5936634 | 0.80 | SMPD1 (0.62) | SMPD1NR1H4MEN1KMT2ANR4A2 | |
| SCHEMBL5936596 | 0.79 | NPC1 (0.57) | SMPD1NR1H4MEN1KMT2ANR4A2 | |
| SCHEMBL5936598 | 0.79 | NR1H4 (0.55) | SMPD1NR1H4MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL28760308 | 0.78 | CTSV (0.50) | MEN1KMT2AMAOB | |
| SCHEMBL13702365 | 0.77 | SMPD1 (0.76) | SMPD1NR1H4MEN1KMT2ANR4A2 | |
| SCHEMBL1123155 | 0.76 | NR4A2 (0.91) | NR1H4MEN1KMT2ANR4A2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1644321-B1 | NEW BENZAMIDES AS PPATY MODULATORS | S A L V A T LAB SA (ES) | 2011-02-09 | — | — | EP | claimed |