Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 4/20 | 0.54 |
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.54 |
| ▸ | CASP3 | P42574 | 1/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.52 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.52 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.52 |
| ▸ | SPHK2 | Q9NRA0 | 3/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.51 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.50 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5720726 | 0.94 | RAB9A (0.60) | NR1H4NPC1RAB9AMEN1KMT2A | |
| SCHEMBL1123450 | 0.91 | SMPD1 (0.59) | NR1H4NPC1RAB9AMEN1KMT2A | |
| SCHEMBL5936596 | 0.88 | NPC1 (0.57) | NR1H4NPC1RAB9AMEN1KMT2A | |
| SCHEMBL5936598 | 0.88 | NR1H4 (0.55) | NR1H4NPC1RAB9AMEN1KMT2A | |
| SCHEMBL5936634 | 0.77 | SMPD1 (0.62) | NR1H4RAB9AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL1123461 | 0.76 | NR4A2 (0.81) | RAB9AMEN1KMT2ASMN1; SMN2RXFP1 | |
| SCHEMBL5936672 | 0.76 | SMPD1 (0.60) | NR1H4NPC1RAB9AMEN1KMT2A | |
| SCHEMBL28760308 | 0.75 | CTSV (0.50) | MEN1KMT2AFFAR1SIRT2LMNA | |
| SCHEMBL27330799 | 0.74 | MGLL (0.50) | NPC1RAB9ASMN1; SMN2CASP3ALDH1A1 | |
| SCHEMBL1122731 | 0.74 | SMN1; SMN2 (0.64) | NPC1RAB9AMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1644321-B1 | NEW BENZAMIDES AS PPATY MODULATORS | S A L V A T LAB SA (ES) | 2011-02-09 | — | — | EP | claimed |