Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.57 |
| ▸ | RAB9A | P51151 | 4/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | CASP3 | P42574 | 1/20 | 0.57 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.57 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.57 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.51 |
| ▸ | SPHK2 | Q9NRA0 | 3/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.50 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.50 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.49 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1122980 | 0.88 | NR1H4 (0.56) | NPC1RAB9ASMN1; SMN2CASP3TAAR1 | |
| SCHEMBL5936598 | 0.87 | NR1H4 (0.55) | NPC1RAB9ASMN1; SMN2CASP3TAAR1 | |
| SCHEMBL5720726 | 0.82 | RAB9A (0.60) | NPC1RAB9ASMN1; SMN2CASP3TAAR1 | |
| SCHEMBL1123450 | 0.79 | SMPD1 (0.59) | NPC1RAB9ASMN1; SMN2NR1H4MEN1 | |
| SCHEMBL5936634 | 0.76 | SMPD1 (0.62) | RAB9ASMN1; SMN2NR1H4MEN1KMT2A | |
| SCHEMBL1123461 | 0.76 | NR4A2 (0.81) | RAB9ASMN1; SMN2MEN1KMT2ARXFP1 | |
| SCHEMBL5936672 | 0.76 | SMPD1 (0.60) | NPC1RAB9ASMN1; SMN2NR1H4MEN1 | |
| SCHEMBL1122731 | 0.74 | SMN1; SMN2 (0.64) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL22192264 | 0.73 | RAB9A (0.94) | NPC1RAB9ASMN1; SMN2CASP3TAAR1 | |
| SCHEMBL11550139 | 0.72 | NR1H4 (0.81) | NPC1RAB9ASMN1; SMN2NR1H4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060160894-A1 | Benzamides as ppar modulators | LABORATORIOS S.A.L.V.A.T.,S.A. (ES) | 2006-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060160894-A1 | Benzamides as ppar modulators | PPARD, PPARA, PPARG | NPC1 3147/4885RAB9A 4567/4885SMN1; SMN2 3984/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.