Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFD | P00746 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.56 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.56 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.55 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | CASP3 | P42574 | 1/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.52 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1123386 | 0.95 | CFD (0.61) | CFDTSHRALDH1A1GAAMEN1 | |
| SCHEMBL1123026 | 0.90 | SMPD1 (0.59) | CFDTSHRALDH1A1GAAMEN1 | |
| SCHEMBL1123136 | 0.85 | SMPD1 (0.60) | CFDTSHRALDH1A1GAAMEN1 | |
| SCHEMBL7713160 | 0.83 | SMPD1 (0.64) | TSHRALDH1A1GAAMEN1KMT2A | |
| SCHEMBL1123169 | 0.80 | SENP7 (0.61) | CFDMEN1KMT2AHDAC1SMN1; SMN2 | |
| SCHEMBL7710629 | 0.80 | KDM4E (0.66) | TSHRALDH1A1GAAMEN1KMT2A | |
| SCHEMBL1122722 | 0.77 | MAOB (0.68) | MEN1KMT2ASMPD1MAOBSMN1; SMN2 | |
| SCHEMBL7076910 | 0.76 | HDAC1 (0.59) | TSHRALDH1A1GAAMEN1KMT2A | |
| SCHEMBL16397074 | 0.76 | CFD (0.65) | CFDTSHRALDH1A1MEN1KMT2A | |
| SCHEMBL1123091 | 0.76 | SMPD1 (0.69) | TSHRALDH1A1GAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1644321-B1 | NEW BENZAMIDES AS PPATY MODULATORS | S A L V A T LAB SA (ES) | 2011-02-09 | — | — | EP | disclosed |