Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 2/20 | 0.60 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.60 |
| ▸ | SUCNR1 | Q9BXA5 | 4/20 | 0.59 |
| ▸ | CFD | P00746 | 1/20 | 0.59 |
| ▸ | F11 | P03951 | 1/20 | 0.59 |
| ▸ | TPSB2 | P20231 | 1/20 | 0.59 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.59 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.59 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.57 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.55 |
| ▸ | MAOB | P27338 | 1/20 | 0.53 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1123026 | 0.94 | SMPD1 (0.59) | SMPD1NR1H4SUCNR1CFDF11 | |
| SCHEMBL1123386 | 0.90 | CFD (0.61) | SMPD1NR1H4CFDHDAC1HDAC8 | |
| SCHEMBL7713160 | 0.87 | SMPD1 (0.64) | SMPD1NR1H4HDAC1HDAC8HDAC6 | |
| SCHEMBL1123496 | 0.85 | CFD (0.60) | SMPD1NR1H4CFDHDAC1HDAC8 | |
| SCHEMBL7710629 | 0.79 | KDM4E (0.66) | SMPD1NR1H4HDAC1HDAC8HDAC6 | |
| SCHEMBL1123091 | 0.77 | SMPD1 (0.69) | SMPD1NR1H4HDAC1HDAC8HDAC6 | |
| SCHEMBL7049305 | 0.77 | SMPD1 (0.60) | SMPD1NR1H4HDAC1HDAC8HDAC6 | |
| SCHEMBL21711305 | 0.77 | NR1H4 (0.75) | NR1H4SUCNR1CFDF11TPSB2 | |
| SCHEMBL5936638 | 0.77 | NR1H4 (0.69) | SMPD1NR1H4ALDH1A1MEN1KMT2A | |
| SCHEMBL6358261 | 0.77 | ALDH1A1 (0.66) | SMPD1NR1H4HDAC1HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1644321-B1 | NEW BENZAMIDES AS PPATY MODULATORS | S A L V A T LAB SA (ES) | 2011-02-09 | — | — | EP | disclosed |