Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 12/20 | 0.38 |
| ▸ | HTR1A | P08908 | 8/20 | 0.38 |
| ▸ | HTR2A | P28223 | 8/20 | 0.38 |
| ▸ | HRH1 | P35367 | 8/20 | 0.38 |
| ▸ | DRD3 | P35462 | 7/20 | 0.38 |
| ▸ | DRD4 | P21917 | 6/20 | 0.38 |
| ▸ | HTR2C | P28335 | 3/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.38 |
| ▸ | HTR7 | P34969 | 3/20 | 0.38 |
| ▸ | HTR2B | P41595 | 3/20 | 0.38 |
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7646399 | 0.72 | POLB (0.47) | HTR1A | |
| SCHEMBL11238944 | 0.72 | DRD2 (0.44) | DRD2HTR1AHTR2AHRH1DRD3 | |
| SCHEMBL11238942 | 0.71 | DRD2 (0.35) | DRD2HTR1AHTR2AHRH1DRD3 | |
| SCHEMBL10854731 | 0.71 | CCR5 (0.39) | HTR1ADRD3ADRA2AADRA1ADRD1 | |
| SCHEMBL11236973 | 0.70 | SLC18A3 (0.51) | DRD2HTR1AHTR2AHRH1DRD3 | |
| SCHEMBL11618588 | 0.70 | HTR2A (0.57) | HTR2AHTR2CHTR7 | |
| SCHEMBL11233227 | 0.70 | SLC6A3 (0.39) | SLC6A3 | |
| SCHEMBL4053345 | 0.70 | EGFR (0.32) | SLC6A3SLC6A4 | |
| SCHEMBL13242104 | 0.70 | SLC6A4 (0.36) | SLC6A4HTR7 | |
| SCHEMBL7653024 | 0.69 | KDM4E (0.47) | DRD2HTR1AHTR2AHRH1DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4366154-A | TRANQUILIZERS; PSYCHOLOGICAL DISORDERS | SANDOZ, INC. (US) | 1982-12-28 | — | — | US | disclosed |