Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.47 |
| ▸ | DRD2 | P14416 | 3/20 | 0.47 |
| ▸ | DRD4 | P21917 | 3/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.47 |
| ▸ | DRD3 | P35462 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | GMNN | O75496 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.47 |
| ▸ | THPO | P40225 | 2/20 | 0.47 |
| ▸ | BLM | P54132 | 2/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4283782 | 0.75 | HTR2A (0.47) | SLC18A3SLC6A3SLC6A2CHRM1DRD2 | |
| SCHEMBL11236719 | 0.74 | DRD2 (0.53) | SLC18A3SLC6A3SLC6A2CHRM1DRD2 | |
| SCHEMBL7295696 | 0.74 | SCN5A (0.58) | SLC6A3SLC6A2CHRM1DRD2DRD4 | |
| SCHEMBL11236713 | 0.73 | DRD2 (0.49) | SLC18A3SLC6A3SLC6A2CHRM1DRD2 | |
| SCHEMBL6153609 | 0.71 | DRD2 (0.50) | SLC6A2DRD2DRD4DRD3ALDH1A1 | |
| SCHEMBL11235162 | 0.70 | DRD2 (0.38) | SLC18A3SLC6A3SLC6A2CHRM1DRD2 | |
| SCHEMBL13504722 | 0.69 | HTR2A (0.59) | SLC6A3SLC6A2CHRM1DRD2DRD4 | |
| SCHEMBL4652287 | 0.69 | CYP3A4 (0.41) | SLC18A3SLC6A3SLC6A2CHRM1DRD2 | |
| SCHEMBL14641553 | 0.69 | CYP3A4 (0.46) | SLC6A3SLC6A2CHRM1DRD2DRD4 | |
| SCHEMBL4282157 | 0.68 | ALDH1A1 (0.55) | SLC6A3SLC6A2CHRM1DRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4366154-A | TRANQUILIZERS; PSYCHOLOGICAL DISORDERS | SANDOZ, INC. (US) | 1982-12-28 | — | — | US | disclosed |