Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.64 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.56 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.56 |
| ▸ | GPR132 | Q9UNW8 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.51 |
| ▸ | ITGAV | P06756 | 1/20 | 0.51 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1123368 | 0.91 | GPR132 (0.60) | PTPN1ITGB3ITGA2BGPR132ITGB1 | |
| SCHEMBL1123050 | 0.90 | PTPN1 (0.69) | PTPN1ITGB3ITGA2BGPR132RAB9A | |
| SCHEMBL1122721 | 0.89 | PTPN1 (0.68) | PTPN1ITGB3ITGA2BGPR132RAB9A | |
| SCHEMBL1123437 | 0.88 | PTPN1 (0.67) | PTPN1ITGB3ITGA2BGPR132RAB9A | |
| SCHEMBL1123282 | 0.83 | PTPN1 (0.58) | PTPN1ITGB3ITGA2BGPR132RAB9A | |
| SCHEMBL7300651 | 0.83 | ITGB3 (0.66) | PTPN1ITGB3ITGA2BGPR132RAB9A | |
| SCHEMBL8165005 | 0.82 | PTPN1 (0.67) | PTPN1RAB9AMEN1ALDH1A1LMNA | |
| SCHEMBL8165003 | 0.82 | PTPN1 (0.67) | PTPN1RAB9AMEN1ALDH1A1LMNA | |
| SCHEMBL1122913 | 0.82 | PTPN1 (0.56) | PTPN1ITGB3ITGA2BGPR132RAB9A | |
| SCHEMBL11043905 | 0.79 | ITGB3 (0.69) | PTPN1ITGB3ITGA2BGPR132RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1644321-B1 | NEW BENZAMIDES AS PPATY MODULATORS | S A L V A T LAB SA (ES) | 2011-02-09 | — | — | EP | disclosed |
| CN-1835914-A | New benzamides as PPAR[upsilon] modulators | S A L V A T LAB SA (ES) | 2006-09-20 | — | — | CN | disclosed |
| US-20060160894-A1 | Benzamides as ppar modulators | LABORATORIOS S.A.L.V.A.T.,S.A. (ES) | 2006-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060160894-A1 | Benzamides as ppar modulators | PPARD, PPARA, PPARG | PTPN1 2708/4885ITGB3 1819/4885ITGA2B 2461/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.