Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 5/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8844863 | 0.84 | SLC7A5 (0.57) | SLC6A3 | |
| SCHEMBL8214893 | 0.82 | ALDH1A1 (0.44) | — | |
| Potassium Ion SCHEMBL8844851 | 0.81 | TPH1 (0.43) | — | |
| SCHEMBL251733 | 0.79 | ANPEP (0.62) | TAAR1SLC6A2SLC6A4SLC6A3MAOA | |
| SCHEMBL5183224 | 0.79 | ANPEP (0.62) | TAAR1SLC6A2SLC6A4SLC6A3MAOA | |
| SCHEMBL2439514 | 0.79 | ANPEP (0.62) | TAAR1SLC6A2SLC6A4SLC6A3MAOA | |
| Dextroamphetamine SCHEMBL3681578 | 0.79 | SLC6A2 (0.63) | TAAR1SLC6A2SLC6A4SLC6A3MAOA | |
| Levamfetamine SCHEMBL4596702 | 0.79 | SLC6A2 (0.63) | TAAR1SLC6A2SLC6A4SLC6A3MAOA | |
| Amphetamine SCHEMBL1030966 | 0.79 | SLC6A2 (0.63) | TAAR1SLC6A2SLC6A4SLC6A3MAOA | |
| Amphetamine SCHEMBL1030967 | 0.79 | SLC6A2 (0.63) | TAAR1SLC6A2SLC6A4SLC6A3MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4338346-A | Non-nutritive sweetener | THE PROCTER & GAMBLE COMPANY (US) | 1982-07-06 | — | — | US | disclosed |
| EP-0013044-A1 | L-aspartyl amide derivatives and their use as sweetening agents | THE PROCTER & GAMBLE COMPANY (US) | 1980-07-09 | — | — | EP | disclosed |