Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.48 |
| ▸ | CES1 | P23141 | 2/20 | 0.48 |
| ▸ | PPARA | Q07869 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | NAAA | Q02083 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 4/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.43 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.43 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.43 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.43 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.43 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.43 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.42 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11241565 | 1.00 | CES2 (0.48) | CES2CES1PPARATSHRALDH1A1 | |
| SCHEMBL11236194 | 0.99 | CES2 (0.46) | CES2CES1PPARATSHRALDH1A1 | |
| SCHEMBL11236197 | 0.99 | CES2 (0.46) | CES2CES1PPARATSHRALDH1A1 | |
| SCHEMBL11228210 | 0.94 | ESR1 (0.45) | CES2CES1PPARATSHRLMNA | |
| SCHEMBL11243823 | 0.88 | LMNA (0.49) | CES2CES1PPARAALDH1A1LMNA | |
| SCHEMBL11243827 | 0.88 | LMNA (0.49) | CES2CES1PPARAALDH1A1LMNA | |
| SCHEMBL11241570 | 0.86 | CES2 (0.48) | CES2CES1PPARATSHRALDH1A1 | |
| SCHEMBL11236201 | 0.84 | GAA (0.47) | CES2CES1PPARATSHRALDH1A1 | |
| SCHEMBL11236778 | 0.82 | SMN1; SMN2 (0.44) | CES2CES1TSHRALDH1A1LMNA | |
| SCHEMBL11228215 | 0.79 | GAA (0.49) | CES2CES1PPARATSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4342760-A | ANTIMICROBIAL AGENTS | FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) | 1982-08-03 | — | — | US | disclosed |
| US-4264597-A | FUNGICIDES | FUJISAWA PHARMACEUTICAL CO., LTD., NO. 3, 4-CHOME, DOSHOMACHI, HIGASHI-KU, OSAKA, JAPAN | 1981-04-28 | — | — | US | disclosed |