SCHEMBL11236261

SCHEMBL11236261

CCCCCCCCCCCCCCCCOc1ccc(C(=O)CC(=O)O)cc1

nearest known ligand 0.71

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.71
TSHR P16473 1/20 0.71
PLA2G4B P0C869 6/20 0.69
RARB P10826 3/20 0.66
THRA P10827 3/20 0.63
THRB P10828 3/20 0.63
PLA2G4A P47712 1/20 0.62
MMP1 P03956 1/20 0.58
L3MBTL1 Q9Y468 1/20 0.58
PPARG P37231 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2866720 0.92 TP53 (0.73) TP53TSHRPLA2G4BRARBTHRA
SCHEMBL7913066 0.90 TP53 (0.70) TP53TSHRPLA2G4BRARBTHRA
SCHEMBL9615413 0.88 RARB (0.64) TP53TSHRPLA2G4BRARBTHRA
SCHEMBL11802071 0.88 TP53 (0.67) TP53TSHRPLA2G4BRARBTHRA
SCHEMBL7636635 0.87 L3MBTL1 (0.69) TP53TSHRPLA2G4BRARBTHRA
SCHEMBL7827962 0.86 THRA (0.70) TP53TSHRPLA2G4BRARBTHRA
SCHEMBL7821751 0.86 THRA (0.70) TP53TSHRPLA2G4BRARBTHRA
SCHEMBL5081632 0.86 THRA (0.70) TP53TSHRPLA2G4BRARBTHRA
SCHEMBL8754682 0.86 THRA (0.70) TP53TSHRPLA2G4BRARBTHRA
SCHEMBL3031625 0.86 TP53 (0.64) TP53TSHRPLA2G4BRARBTHRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0001650-B1 ACYLACETANILIDE COMPOUNDS AND THEIR USE AS YELLOW FORMING COLOUR COUPLERS FOR SILVER HALIDE PHOTOGRAPHY AGFA-GEVAERT N.V. (BE) 1982-07-28 EP disclosed
US-4201584-A Silver halide elements containing yellow forming color couplers for silver halide photography AGFA-GEVAERT N.V. (BE) 1980-05-06 US disclosed
EP-0001650-A1 Acylacetanilide compounds and their use as yellow forming colour couplers for silver halide photography AGFA-GEVAERT N.V. (BE) 1979-05-02 EP disclosed