SCHEMBL7636635

SCHEMBL7636635

CCCCOc1ccc(C(=O)CC(=O)c2ccc(OCCCC)cc2)cc1

nearest known ligand 0.69

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.69
MMP1 P03956 1/20 0.69
TP53 P04637 1/20 0.64
TSHR P16473 1/20 0.64
PLA2G4B P0C869 2/20 0.62
THRA P10827 2/20 0.60
THRB P10828 2/20 0.60
PLK1 P53350 1/20 0.59
RARB P10826 3/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7913066 0.96 TP53 (0.70) L3MBTL1MMP1TP53TSHRPLA2G4B
SCHEMBL2866720 0.95 TP53 (0.73) L3MBTL1MMP1TP53TSHRPLA2G4B
SCHEMBL7629094 0.93 MMP1 (0.61) L3MBTL1MMP1TP53TSHRPLA2G4B
SCHEMBL16203310 0.93 MAPT (0.68) L3MBTL1MMP1TP53TSHRPLA2G4B
SCHEMBL7627368 0.93 MMP1 (0.61) L3MBTL1MMP1TP53TSHRPLA2G4B
SCHEMBL7632695 0.92 L3MBTL1 (0.74) L3MBTL1MMP1TP53TSHRTHRB
SCHEMBL2350431 0.92 MAPT (0.72) L3MBTL1MMP1TP53TSHRPLA2G4B
SCHEMBL7631880 0.92 MMP1 (0.60) L3MBTL1MMP1TP53TSHRPLA2G4B
SCHEMBL7632738 0.90 ALDH1A1 (0.60) L3MBTL1MMP1TP53TSHRPLA2G4B
SCHEMBL7637309 0.90 MMP1 (0.58) L3MBTL1MMP1TP53TSHRPLA2G4B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6448304-B1 POLYURETHANE, POLYTHIOURETHANE OR DIETHYLENE GLYCOL BISALLYLCARBONATE POLYMER; DIPPING IN SOLUTION CONTAINING A DIBENZOYLMETHANE OR A BENZOTRIZOLE COMPOUND; PLASTIC LENS FOR SPECTACLES WHICH ABSORBS ULTRAVIOLET RAYS; LOW YELLOWNESS HOYA CORPORATION (JP) 2002-09-10 US disclosed