SCHEMBL2866720

SCHEMBL2866720

CCCCCCCCCOc1ccc(C(=O)CC(=O)c2ccc(OCCCCCCCCC)cc2)cc1

nearest known ligand 0.73

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.73
TSHR P16473 1/20 0.73
PLA2G4B P0C869 5/20 0.71
THRA P10827 4/20 0.68
THRB P10828 4/20 0.68
RARB P10826 3/20 0.67
PLA2G4A P47712 1/20 0.63
MMP1 P03956 1/20 0.63
L3MBTL1 Q9Y468 1/20 0.63
GAA P10253 1/20 0.61
NR5A1 Q13285 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7913066 0.98 TP53 (0.70) TP53TSHRPLA2G4BTHRATHRB
SCHEMBL7636635 0.95 L3MBTL1 (0.69) TP53TSHRPLA2G4BTHRATHRB
SCHEMBL2355796 0.92 MAPT (0.66) TP53TSHRPLA2G4BTHRATHRB
SCHEMBL2356406 0.92 MAPT (0.66) TP53TSHRPLA2G4BTHRATHRB
SCHEMBL11236261 0.92 TP53 (0.71) TP53TSHRPLA2G4BTHRATHRB
SCHEMBL11802071 0.92 TP53 (0.67) TP53TSHRPLA2G4BTHRATHRB
SCHEMBL2350770 0.91 MAPT (0.68) TP53TSHRPLA2G4BTHRATHRB
SCHEMBL3031625 0.90 TP53 (0.64) TP53TSHRPLA2G4BTHRATHRB
SCHEMBL17284859 0.90 TP53 (0.73) TP53TSHRPLA2G4BTHRATHRB
SCHEMBL13267786 0.90 TP53 (0.73) TP53TSHRPLA2G4BTHRATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050245673-A1 Care and/or make-up cosmetic composition structured with silicone polymers and organogelling agents, in rigid form L'OREAL S.A. (FR) 2005-11-03 US claimed
CN-1658819-A Care and/or make-up cosmetic composition structured with silicone polymers and organogelling agents, in rigid form OREAL (FR) 2005-08-24 CN claimed
EP-1515684-A2 CARE AND/OR MAKE-UP COSMETIC COMPOSITION STRUCTURED WITH SILICONE POLYMERS AND ORGANOGELLING AGENTS, IN RIGID FORM L'OREAL (FR) 2005-03-23 EP claimed
WO-2003105788-A2 CARE AND/OR MAKE-UP COSMETIC COMPOSITION STRUCTURED WITH SILICONE POLYMERS AND ORGANOGELLING AGENTS, IN RIGID FORM L'OREAL (FR) 2003-12-24 WO claimed
US-9180195-B2 Controlled release gels NANO FIBER MATRICES B.V. (NL) 2015-11-10 US disclosed
US-7820146-B2 Care and/or make-up cosmetic composition structured with silicone polymers and organogelling agents, in rigid form L'OREAL S.A. (FR) 2010-10-26 US disclosed
US-20090169498-A1 Controlled Release Gels NANO FIBER MATRICES B.V. (NL) 2009-07-02 US disclosed
US-20080057011-A1 Composition structured with a polymer containing a heteroatom and an Organogelator L'OREAL S.A., 2008-03-06 US disclosed
US-20050245673-A1 Care and/or make-up cosmetic composition structured with silicone polymers and organogelling agents, in rigid form L'OREAL S.A. (FR) 2005-11-03 US disclosed
CN-1658819-A Care and/or make-up cosmetic composition structured with silicone polymers and organogelling agents, in rigid form OREAL (FR) 2005-08-24 CN disclosed
US-20050158260-A1 Cosmetic composition containing a polyorganosiloxane polymer L'OREAL (FR) 2005-07-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080057011-A1 Composition structured with a polymer containing a heteroatom and an Organogelator CUTA, FABP4, PARG TP53 1092/4885TSHR 3188/4885PLA2G4B 750/4885
US-20090169498-A1 Controlled Release Gels PGA5, SUCLG1, CDC37 TP53 2819/4885TSHR 3402/4885PLA2G4B 877/4885
US-20050158260-A1 Cosmetic composition containing a polyorganosiloxane polymer SQLE, CUTA, FDFT1 TP53 720/4885TSHR 3496/4885PLA2G4B 1218/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.