Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMOX1 | P09601 | 1/20 | 0.57 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.56 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.56 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.56 |
| ▸ | TBXAS1 | P24557 | 4/20 | 0.55 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | NOS1 | P29475 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11251579 | 0.86 | CYP2A6 (0.58) | CYP19A1CYP11B1CYP11B2TBXAS1EGLN3 | |
| SCHEMBL11236348 | 0.86 | CYP19A1 (0.56) | CYP19A1CYP11B1CYP11B2TBXAS1EGLN3 | |
| SCHEMBL11259784 | 0.86 | TBXAS1 (0.55) | TBXAS1EGLN3 | |
| SCHEMBL11231149 | 0.85 | EGLN3 (0.58) | CYP19A1CYP11B1CYP11B2TBXAS1EGLN3 | |
| SCHEMBL11260419 | 0.83 | TBXAS1 (0.59) | TBXAS1EGLN3 | |
| SCHEMBL11242023 | 0.83 | KMT2A (0.53) | TBXAS1EGLN3 | |
| SCHEMBL11240600 | 0.82 | CYP19A1 (0.60) | CYP19A1CYP11B1TBXAS1 | |
| SCHEMBL11251100 | 0.82 | NOS1 (0.53) | HMOX1TBXAS1EGLN3NOS1 | |
| SCHEMBL11255655 | 0.81 | TBXAS1 (0.56) | HMOX1CYP19A1TBXAS1 | |
| SCHEMBL11249784 | 0.78 | TBXAS1 (0.65) | CYP19A1TBXAS1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4359475-A | SPERMICIDES, MICROBIOCIDES OR ANTICONVULSANTS | SYNTEX (U.S.A.) INC. (US) | 1982-11-16 | — | — | US | disclosed |
| EP-0049565-A2 | Derivatives of substituted N-alkylimidazoles, their preparation and pharmaceutical compositions containing them | SYNTEX (U.S.A.) INC. (US) | 1982-04-14 | — | — | EP | disclosed |
| US-4321272-A | Derivatives of substituted N-alkylimidazoles | SYNTEX (U.S.A.) INC. (US) | 1982-03-23 | — | — | US | disclosed |