Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TGM2 | P21980 | 1/20 | 0.39 |
| ▸ | ABCC9 | O60706 | 2/20 | 0.38 |
| ▸ | KCNJ11 | Q14654 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8854243 | 0.90 | ABCC9 (0.40) | RAB9AKDM4EPOLBMAPTHTT | |
| SCHEMBL13523189 | 0.82 | GAA (0.43) | RAB9ANPC1KDM4EMAPTALDH1A1 | |
| SCHEMBL8898313 | 0.81 | SMN1; SMN2 (0.52) | TDP1RAB9ANPC1KDM4EPOLB | |
| SCHEMBL678436 | 0.81 | TDP1 (0.56) | TDP1RAB9ANPC1KDM4EPOLB | |
| SCHEMBL1108190 | 0.81 | MAPT (0.47) | RAB9ANPC1KDM4EPOLBMAPT | |
| SCHEMBL11227303 | 0.80 | NPC1 (0.50) | TDP1RAB9ANPC1KDM4EPOLB | |
| SCHEMBL24726744 | 0.80 | CYP1A2 (0.46) | RAB9ANPC1KDM4EMAPTTP53 | |
| SCHEMBL4259667 | 0.80 | CYP1A2 (0.46) | RAB9ANPC1KDM4EMAPTTP53 | |
| SCHEMBL18520538 | 0.80 | CYP1A2 (0.46) | RAB9ANPC1KDM4EMAPTTP53 | |
| SCHEMBL3056662 | 0.77 | TDP1 (0.52) | TDP1RAB9ANPC1KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110263901-A1 | Process of Preparation of Proguanil | USV LTD. (IN) | 2011-10-27 | — | — | US | disclosed |
| US-20110263901-A1 | Process of Preparation of Proguanil | USV LTD. (IN) | 2011-10-27 | — | — | US | disclosed |
| US-4347310-A | INCREASED PHOTOSENZITIVITY USING GUANIDINE DERIVTIVES AS SENSITIZERS; PHOTOSTABILITY; STORAGE STABILITY | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1982-08-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110263901-A1 | Process of Preparation of Proguanil | GCG, PREP, G6PD | TDP1 3906/4885RAB9A 641/4885NPC1 2777/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.