SCHEMBL4259667

SCHEMBL4259667

N#CNC(=N)Nc1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.46
CYP2C19 P33261 1/20 0.46
ABCC9 O60706 1/20 0.45
KCNJ11 Q14654 1/20 0.45
ALDH1A1 P00352 5/20 0.44
KDM4E B2RXH2 2/20 0.43
GAA P10253 2/20 0.43
P2RX7 Q99572 2/20 0.43
TAS2R38 P59533 3/20 0.41
HSD17B10 Q99714 3/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
TP53 P04637 2/20 0.41
TSHR P16473 2/20 0.41
EPHX1 P07099 1/20 0.41
EPHX2 P34913 1/20 0.41
CDK9 P50750 1/20 0.41
CLK4 Q9HAZ1 1/20 0.41
CYP3A4 P08684 1/20 0.41
MAPT P10636 2/20 0.40
MEN1 O00255 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18520538 1.00 CYP1A2 (0.46) CYP1A2CYP2C19ABCC9KCNJ11ALDH1A1
SCHEMBL24726744 1.00 CYP1A2 (0.46) CYP1A2CYP2C19ABCC9KCNJ11ALDH1A1
SCHEMBL8854243 0.89 ABCC9 (0.40) CYP1A2CYP2C19ABCC9KCNJ11ALDH1A1
SCHEMBL13523189 0.82 GAA (0.43) ABCC9KCNJ11ALDH1A1KDM4EGAA
SCHEMBL11236635 0.80 TDP1 (0.44) CYP1A2CYP2C19ABCC9KCNJ11ALDH1A1
SCHEMBL160934 0.80 CYP3A4 (0.48) CYP1A2CYP2C19ABCC9KCNJ11ALDH1A1
SCHEMBL1108190 0.80 MAPT (0.47) ALDH1A1KDM4EGAASMN1; SMN2TP53
SCHEMBL35172 0.79 HSD17B10 (0.55) ALDH1A1KDM4EGAATAS2R38HSD17B10
Benzene SCHEMBL27899223 0.79 HSD17B10 (0.55) ALDH1A1KDM4EGAATAS2R38HSD17B10
SCHEMBL20163213 0.79 HSD17B10 (0.55) ALDH1A1KDM4EGAATAS2R38HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 105 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113149917-B Preparation method of triazine compound 浙江工业大学 2023-01-10 CN claimed
CN-113149917-A Preparation method of triazine compound 浙江工业大学 2021-07-23 CN claimed
CN-1198489-A Composition having no formol used for nonwoven cloth ROHM & HAAS (US) 1998-11-11 CN claimed
US-4347310-A INCREASED PHOTOSENZITIVITY USING GUANIDINE DERIVTIVES AS SENSITIZERS; PHOTOSTABILITY; STORAGE STABILITY ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1982-08-31 US claimed
US-20250235390-A1 Composition and Process for Treating a Disorder in the Oral Cavity of a Mammal SOLVENTUM INTELLECTUAL PROPERTIES COMPANY 2025-07-24 US disclosed
EP-3534867-B1 MEDICAL COMPOSITION CONTAINING GUANIDINYL-CONTAINING POLYMER(S) AND CARRAGEENANE(S) SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2025-06-04 EP disclosed
EP-3534866-B1 METHOD OF DENTAL RETRACTION WITH COMPOSITION WITH GUANIDINYL-CONTAINING POLYMER SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2025-05-28 EP disclosed
US-12295369-B2 Articles containing a crosslinked guanidinyl-containing polymer and uses thereof SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2025-05-13 US disclosed
US-20250145760-A1 EPOXY RESIN COMPOSITIONS COMPRISING DICYANDIAMID CURING AGENT 3M INNOVATIVE PROPERTIES COMPANY 2025-05-08 US disclosed
US-20250082440-A1 Composition for Isolating Tissue SOLVENTUM INTELLECTUAL PROPERTIES COMPANY 2025-03-13 US disclosed
CN-119072512-A Epoxy resin composition comprising dicyandiamide curing agent 3M创新有限公司 2024-12-03 CN disclosed
EP-4442727-A1 EPOXY RESIN COMPOSITIONS COMPRISING A LEWIS ACID 3M Innovative Properties Company (US) 2024-10-09 EP disclosed
CN-1104520-C Composition having no formol used for nonwoven cloth ROHM & HAAS (US) 2003-04-02 CN disclosed
CN-1198489-A Composition having no formol used for nonwoven cloth ROHM & HAAS (US) 1998-11-11 CN disclosed
US-4347310-A INCREASED PHOTOSENZITIVITY USING GUANIDINE DERIVTIVES AS SENSITIZERS; PHOTOSTABILITY; STORAGE STABILITY ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1982-08-31 US disclosed
US-4265905-A FOR AUTOIMMUNE DISEASES MERCK & CO., INC. (US) 1981-05-05 US disclosed
US-4202903-A Acyl cyanoguanidines for treating rheumatoid arthritis MERCK & CO., INC. (US) 1980-05-13 US disclosed
US-4024105-A PLASTICS HOECHST AKTIENGESELLSCHAFT (DT) 1977-05-17 US disclosed
US-3996232-A ANTIULCER AGENTS WILLIAM H. RORER, INC. (US) 1976-12-07 US disclosed
US-3969292-A Stabilized molding compositions based on poly(oxymethylene) HOECHST AKTIENGESELLSCHAFT (DT) 1976-07-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12295369-B2 Articles containing a crosslinked guanidinyl-containing polymer and uses thereof C5, YTHDC1, PRMT1 CYP1A2 1588/4885CYP2C19 2191/4885ABCC9 4039/4885
US-20250145760-A1 EPOXY RESIN COMPOSITIONS COMPRISING DICYANDIAMID CURING AGENT DDAH1, PHOSPHO1, QDPR CYP1A2 4049/4885CYP2C19 3755/4885ABCC9 2717/4885
US-20250235390-A1 Composition and Process for Treating a Disorder in the Oral Cavity of a Mammal GSDMD, PIGS, GANC CYP1A2 4378/4885CYP2C19 2713/4885ABCC9 612/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.