Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 11/20 | 0.49 |
| ▸ | HTR1A | P08908 | 8/20 | 0.49 |
| ▸ | HTR2A | P28223 | 8/20 | 0.49 |
| ▸ | HRH1 | P35367 | 8/20 | 0.49 |
| ▸ | DRD4 | P21917 | 5/20 | 0.49 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 8/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.41 |
| ▸ | HTR2B | P41595 | 4/20 | 0.41 |
| ▸ | HTR2C | P28335 | 3/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.41 |
| ▸ | DRD1 | P21728 | 2/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11245054 | 0.83 | SLC18A3 (0.43) | DRD2HTR1AHTR2AHRH1DRD4 | |
| SCHEMBL11236719 | 0.78 | DRD2 (0.53) | DRD2HTR1AHTR2AHRH1DRD4 | |
| SCHEMBL11236973 | 0.73 | SLC18A3 (0.51) | DRD2HTR1AHTR2AHRH1DRD4 | |
| SCHEMBL11241625 | 0.70 | SLC18A3 (0.47) | DRD2HTR1AHTR2AHRH1DRD4 | |
| SCHEMBL904855 | 0.63 | OPRL1 (0.69) | DRD2HTR1AHTR2AHRH1DRD4 | |
| SCHEMBL9053117 | 0.63 | DRD2 (0.77) | DRD2HTR1AHTR2AHRH1DRD4 | |
| SCHEMBL1206358 | 0.61 | DRD2 (0.78) | DRD2HTR1AHTR2AHRH1DRD4 | |
| SCHEMBL4283782 | 0.61 | HTR2A (0.47) | DRD2HTR1AHTR2AHRH1DRD4 | |
| SCHEMBL4379525 | 0.61 | DRD3 (0.58) | DRD2HTR1AHTR2AHRH1DRD4 | |
| SCHEMBL12760839 | 0.61 | LMNA (0.48) | MEN1ALDH1A1LMNATSHROPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4366154-A | TRANQUILIZERS; PSYCHOLOGICAL DISORDERS | SANDOZ, INC. (US) | 1982-12-28 | — | — | US | claimed |