Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.39 |
| ▸ | GHSR | Q92847 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 5/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 4/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 6/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11380867 | 0.88 | PGR (0.37) | PGRPDK2GHSRMEN1KMT2A | |
| SCHEMBL11441222 | 0.87 | RPS6KA2 (0.40) | PGRMEN1KMT2AALDH1A1POLB | |
| SCHEMBL11377390 | 0.84 | CYP3A4 (0.44) | PDK2ALDH1A1NPC1RAB9APOLB | |
| SCHEMBL11364773 | 0.83 | RPS6KA2 (0.39) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL11440071 | 0.83 | RPS6KA2 (0.37) | PDK2MEN1KMT2AALDH1A1POLB | |
| SCHEMBL11375946 | 0.83 | ALOX15 (0.38) | PGRMEN1KMT2AALDH1A1POLB | |
| SCHEMBL11379754 | 0.81 | MAPT (0.40) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL11369427 | 0.80 | NPC1 (0.40) | PDK2GHSRMEN1KMT2AALDH1A1 | |
| SCHEMBL11367714 | 0.80 | MAPT (0.39) | PGRGHSRMEN1KMT2AALDH1A1 | |
| SCHEMBL11236725 | 0.80 | MAPT (0.39) | PGRGHSRMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4255577-A | Process and intermediates for preparing 3-[4-(disubstituted-amino)phenyl] or | STERLING DRUG INC. (US) | 1981-03-10 | — | — | US | disclosed |
| US-4200313-A | Carbonless duplicating systems | STERLING DRUG INC. (US) | 1980-04-29 | — | — | US | disclosed |
| US-4187223-A | 3-[4-(Disubstituted-amino)phenyl]-3-(diphenylamino)phthalides | STERLING DRUG INC. (US) | 1980-02-05 | — | — | US | disclosed |