Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.61 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | IDH1 | O75874 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11233308 | 0.89 | FFAR1 (0.65) | FFAR1FFAR4MAPTTHRBHTT | |
| SCHEMBL11249779 | 0.89 | FFAR1 (0.71) | FFAR1FFAR4THRBHTTALDH1A1 | |
| SCHEMBL11246781 | 0.86 | FFAR1 (0.60) | FFAR1FFAR4MAPTTHRBALDH1A1 | |
| SCHEMBL701131 | 0.85 | ALDH1A1 (0.61) | MAPTTHRBHTTALDH1A1POLB | |
| SCHEMBL11240957 | 0.84 | FFAR1 (0.67) | FFAR1FFAR4MAPTTHRBHTT | |
| SCHEMBL29129866 | 0.84 | MAPT (0.64) | FFAR1MAPTHTTALDH1A1L3MBTL1 | |
| SCHEMBL9593360 | 0.83 | ALDH1A1 (0.62) | MAPTTHRBHTTALDH1A1POLB | |
| SCHEMBL29129887 | 0.82 | MAPT (0.73) | FFAR1MAPTHTTPOLBL3MBTL1 | |
| SCHEMBL27529186 | 0.81 | MAPT (0.75) | FFAR1FFAR4MAPTHTTALDH1A1 | |
| SCHEMBL25190960 | 0.80 | NPSR1 (0.67) | FFAR1FFAR4MAPTTHRBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4362892-A | ARALKYLANILINES, ANTICHOLESTEROL AGENTS | BEECHAM GROUP LIMITED (GB) | 1982-12-07 | — | — | US | disclosed |
| US-4206145-A | ALKANOYL-SUBSTITUTED ARALKYLAMINES | BEECHAM GROUP LIMITED (GB) | 1980-06-03 | — | — | US | disclosed |