Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 3/20 | 0.67 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.67 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 1/20 | 0.48 |
| ▸ | MLYCD | O95822 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11233308 | 0.87 | FFAR1 (0.65) | FFAR1FFAR4RXFP1MEN1KMT2A | |
| SCHEMBL11242235 | 0.87 | FFAR1 (0.80) | FFAR1FFAR4RXFP1HDAC1HDAC8 | |
| SCHEMBL11236732 | 0.84 | FFAR1 (0.61) | FFAR1FFAR4RXFP1HDAC1MAPT | |
| SCHEMBL30412285 | 0.83 | MEN1 (0.59) | MEN1KMT2AHDAC1MAPTHDAC8 | |
| SCHEMBL265041 | 0.83 | MEN1 (0.59) | MEN1KMT2AHDAC1MAPTHDAC8 | |
| SCHEMBL11235397 | 0.81 | FFAR1 (0.70) | FFAR1FFAR4RXFP1MEN1KMT2A | |
| SCHEMBL11244569 | 0.80 | FFAR1 (0.76) | FFAR1FFAR4RXFP1MEN1KMT2A | |
| Formaldehyde SCHEMBL9181082 | 0.80 | MEN1 (0.56) | MEN1KMT2AHDAC1MAPTHDAC8 | |
| SCHEMBL9238416 | 0.79 | FFAR1 (0.61) | FFAR1FFAR4RXFP1MEN1KMT2A | |
| SCHEMBL11246781 | 0.79 | FFAR1 (0.60) | FFAR1FFAR4MEN1KMT2AHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4362892-A | ARALKYLANILINES, ANTICHOLESTEROL AGENTS | BEECHAM GROUP LIMITED (GB) | 1982-12-07 | — | — | US | disclosed |
| US-4206145-A | ALKANOYL-SUBSTITUTED ARALKYLAMINES | BEECHAM GROUP LIMITED (GB) | 1980-06-03 | — | — | US | disclosed |