Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 13/20 | 0.71 |
| ▸ | FFAR4 | Q5NUL3 | 7/20 | 0.71 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | GNA15 | P30679 | 1/20 | 0.47 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.47 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SYK | P43405 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11244569 | 0.90 | FFAR1 (0.76) | FFAR1FFAR4THRBKDM4EGNA15 | |
| SCHEMBL11236732 | 0.89 | FFAR1 (0.61) | FFAR1FFAR4THRBKDM4ENPSR1 | |
| SCHEMBL901880 | 0.86 | FFAR4 (0.55) | FFAR1FFAR4THRBEPHX2KDM4E | |
| SCHEMBL11242235 | 0.85 | FFAR1 (0.80) | FFAR1FFAR4GNA15PTGER3TDP1 | |
| SCHEMBL11246781 | 0.84 | FFAR1 (0.60) | FFAR1FFAR4THRBKDM4ENPSR1 | |
| SCHEMBL11249758 | 0.83 | RXFP1 (0.51) | FFAR1FFAR4THRBEPHX2KDM4E | |
| SCHEMBL16839651 | 0.80 | THRB (0.58) | FFAR1FFAR4THRBKDM4ENPSR1 | |
| SCHEMBL11233308 | 0.80 | FFAR1 (0.65) | FFAR1FFAR4THRBKDM4ETDP1 | |
| SCHEMBL11248054 | 0.78 | CYP4F2 (0.56) | FFAR1FFAR4KDM4ECYP4F2CYP4A11 | |
| SCHEMBL25190960 | 0.78 | NPSR1 (0.67) | FFAR1FFAR4THRBKDM4ENPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4362892-A | ARALKYLANILINES, ANTICHOLESTEROL AGENTS | BEECHAM GROUP LIMITED (GB) | 1982-12-07 | — | — | US | disclosed |
| US-4206145-A | ALKANOYL-SUBSTITUTED ARALKYLAMINES | BEECHAM GROUP LIMITED (GB) | 1980-06-03 | — | — | US | disclosed |