Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | CETP | P11597 | 3/20 | 0.45 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | SIRT2 | Q8IXJ6 | 5/20 | 0.44 |
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.44 |
| ▸ | SIRT3 | Q9NTG7 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23072450 | 0.90 | ALDH1A1 (0.64) | ALDH1A1MAPK1L3MBTL1KMT2AMAPT | |
| SCHEMBL11236735 | 0.88 | HPGD (0.53) | ALDH1A1MEN1KMT2AHPGDCETP | |
| SCHEMBL11237791 | 0.88 | HPGD (0.53) | ALDH1A1MEN1KMT2AHPGDCETP | |
| SCHEMBL11236862 | 0.88 | HPGD (0.53) | ALDH1A1MEN1KMT2AHPGDCETP | |
| SCHEMBL11235830 | 0.88 | HPGD (0.53) | ALDH1A1MEN1KMT2AHPGDCETP | |
| SCHEMBL11240005 | 0.88 | HPGD (0.45) | ALDH1A1MAPK1L3MBTL1MEN1KMT2A | |
| SCHEMBL11487844 | 0.85 | LMNA (0.47) | ALDH1A1MAPK1MEN1KMT2AHPGD | |
| SCHEMBL11240923 | 0.85 | PAM (0.51) | ALDH1A1TLR7MAPT | |
| SCHEMBL22315768 | 0.83 | ALDH1A1 (0.49) | ALDH1A1MAPK1L3MBTL1MEN1KMT2A | |
| SCHEMBL28377661 | 0.83 | ALDH1A1 (0.66) | ALDH1A1MAPK1L3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4348399-A | Antiatherosclerotic and hypolipidemic 4-(monoalkylamino)phenyl alkane, alkene and alkyne carbinols, aldehydes, carboxylic acids and derivatives | AMERICAN CYANAMID COMPANY (US) | 1982-09-07 | — | — | US | disclosed |