Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 1.00 |
| ▸ | RAB9A | P51151 | 3/20 | 1.00 |
| ▸ | GAA | P10253 | 3/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 3/20 | 1.00 |
| ▸ | MAPT | P10636 | 2/20 | 1.00 |
| ▸ | MEN1 | O00255 | 2/20 | 1.00 |
| ▸ | HTT | P42858 | 7/20 | 0.66 |
| ▸ | LMNA | P02545 | 6/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.66 |
| ▸ | HPGD | P15428 | 1/20 | 0.66 |
| ▸ | MTOR | P42345 | 1/20 | 0.66 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.66 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.66 |
| ▸ | EGFR | P00533 | 4/20 | 0.59 |
| ▸ | GALR3 | O60755 | 2/20 | 0.59 |
| ▸ | NR2F2 | P24468 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | ALPG | P10696 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2879204 | 0.80 | RAB9A (0.66) | SMN1; SMN2RAB9AGAAKMT2AMAPT | |
| SCHEMBL29496542 | 0.80 | HTT (1.00) | SMN1; SMN2RAB9AGAAKMT2AMAPT | |
| SCHEMBL13283266 | 0.80 | HTT (1.00) | SMN1; SMN2RAB9AGAAKMT2AMAPT | |
| SCHEMBL31197281 | 0.80 | HTT (1.00) | SMN1; SMN2RAB9AGAAKMT2AMAPT | |
| SCHEMBL22097291 | 0.78 | HTT (0.72) | SMN1; SMN2RAB9AGAAKMT2AMAPT | |
| SCHEMBL10061697 | 0.77 | SMN1; SMN2 (0.67) | SMN1; SMN2RAB9AGAAKMT2AMAPT | |
| SCHEMBL9287754 | 0.77 | SUMO3 (0.72) | SMN1; SMN2RAB9AGAAKMT2AMAPT | |
| SCHEMBL4980648 | 0.75 | EGFR (0.62) | SMN1; SMN2RAB9AGAAKMT2AMAPT | |
| SCHEMBL7612718 | 0.75 | EGFR (1.00) | SMN1; SMN2RAB9AKMT2AMAPTHTT | |
| SCHEMBL29898477 | 0.75 | LMNA (0.75) | SMN1; SMN2RAB9AGAAKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4331667-A | TICK CONTROL IN SHEEP AND CATTLE | SANDOZ LTD. (CH) | 1982-05-25 | — | — | US | disclosed |
| US-4331667-A | TICK CONTROL IN SHEEP AND CATTLE | SANDOZ LTD. (CH) | 1982-05-25 | — | — | US | disclosed |