Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | TOP2A | P11388 | 2/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | DGKA | P23743 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.32 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.32 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11237465 | 0.86 | CYP1A2 (0.48) | ALDH1A1TOP2AKDM4ECYP1A2L3MBTL1 | |
| SCHEMBL11232403 | 0.83 | KDM4E (0.33) | ALDH1A1GLAHTR2CDGKAKDM4E | |
| SCHEMBL11239070 | 0.80 | TSHR (0.46) | ALDH1A1KDM4EEPHX2MAPTLMNA | |
| SCHEMBL11239489 | 0.77 | LMNA (0.43) | ALDH1A1EPHX2MAPTLMNA | |
| SCHEMBL11222761 | 0.75 | LMNA (0.33) | ALDH1A1GLAKDM4ELMNA | |
| SCHEMBL11190223 | 0.74 | DGKA (0.50) | ALDH1A1HTR2CDGKAEPHX2MAPT | |
| SCHEMBL11231987 | 0.74 | DGKA (0.46) | ALDH1A1GLATOP2AHTR2CDGKA | |
| SCHEMBL11239281 | 0.73 | TOP2A (0.42) | ALDH1A1GLATOP2AHTR2CDGKA | |
| SCHEMBL11233597 | 0.73 | NAAA (0.42) | ALDH1A1HTR2CDGKAMAPTTHRB | |
| SCHEMBL8421892 | 0.73 | DGKA (0.50) | HTR2CDGKAMAPTLMNADNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4315846-A | FUNGICIDES | TOKYO ORGANIC CHEMICAL INDUSTRIES, LTD. (JP) | 1982-02-16 | — | — | US | disclosed |
| EP-0037861-A1 | Salts of alkylenebisdithiocarbamic acid derivatives, processes for their preparation, fungicidal compositions containing them and methods of combating fungi | TOKYO ORGANIC CHEMICAL INDUSTRIES, LTD. (JP) | 1981-10-21 | — | — | EP | disclosed |