Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ERCC1 | P07992 | 2/20 | 0.44 |
| ▸ | ERCC4 | Q92889 | 2/20 | 0.44 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | BLM | P54132 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | APEX1 | P27695 | 2/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14621781 | 0.80 | NPSR1 (0.69) | NPSR1L3MBTL1APOBEC3AAPOBEC3GALDH1A1 | |
| SCHEMBL14622003 | 0.79 | L3MBTL1 (0.56) | NPSR1L3MBTL1APOBEC3AAPOBEC3GALDH1A1 | |
| Hydrochloric Acid SCHEMBL2767719 | 0.79 | NPSR1 (0.68) | NPSR1L3MBTL1APOBEC3AAPOBEC3GKDM4E | |
| SCHEMBL10220439 | 0.73 | APOBEC3A (0.50) | NPSR1L3MBTL1APOBEC3AAPOBEC3GALDH1A1 | |
| SCHEMBL19700917 | 0.71 | ALOX15 (0.43) | ERCC1ERCC4KDM4EHSD17B10ALDH1A1 | |
| Hydrochloric Acid SCHEMBL9425023 | 0.71 | NPSR1 (0.50) | NPSR1L3MBTL1ERCC1ERCC4MAPT | |
| Trifluoromethanesulfonic Acid SCHEMBL5674195 | 0.70 | L3MBTL1 (0.56) | NPSR1L3MBTL1APOBEC3AAPOBEC3GALDH1A1 | |
| Water SCHEMBL9425668 | 0.70 | CYP2D6 (0.49) | NPSR1L3MBTL1ERCC1ERCC4MAPT | |
| SCHEMBL13934018 | 0.70 | NPSR1 (0.84) | NPSR1L3MBTL1ALDH1A1MAPTKMT2A | |
| SCHEMBL14621511 | 0.70 | APOBEC3A (0.58) | NPSR1L3MBTL1APOBEC3AAPOBEC3GKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4338436-A | ANTIBIOTICS | ELI LILLY AND COMPANY (US) | 1982-07-06 | — | — | US | disclosed |
| US-4338439-A | BACTERICIDAL ANTIBIOTICS | ELI LILLY AND COMPANY (US) | 1982-07-06 | — | — | US | disclosed |