Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.68 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.54 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14621781 | 0.98 | NPSR1 (0.69) | NPSR1L3MBTL1LMNAAPOBEC3AAPOBEC3G | |
| Hydrochloric Acid SCHEMBL2805432 | 0.87 | NPSR1 (0.71) | NPSR1L3MBTL1LMNACYP2D6ALDH1A1 | |
| Trifluoromethanesulfonic Acid SCHEMBL5674195 | 0.86 | L3MBTL1 (0.56) | NPSR1L3MBTL1LMNAAPOBEC3AAPOBEC3G | |
| Hydrochloric Acid SCHEMBL6682576 | 0.85 | NPSR1 (0.69) | NPSR1L3MBTL1LMNACYP2D6ALDH1A1 | |
| Hydrochloric Acid SCHEMBL6682577 | 0.85 | NPSR1 (0.69) | NPSR1L3MBTL1LMNACYP2D6ALDH1A1 | |
| Hydrochloric Acid SCHEMBL29676296 | 0.85 | NPSR1 (0.69) | NPSR1L3MBTL1LMNACYP2D6ALDH1A1 | |
| SCHEMBL30057272 | 0.85 | NPSR1 (0.73) | NPSR1L3MBTL1LMNACYP2D6ALDH1A1 | |
| SCHEMBL125500 | 0.85 | NPSR1 (0.73) | NPSR1L3MBTL1LMNACYP2D6ALDH1A1 | |
| SCHEMBL14622003 | 0.84 | L3MBTL1 (0.56) | NPSR1L3MBTL1LMNAAPOBEC3AAPOBEC3G | |
| Hydrochloric Acid SCHEMBL34474900 | 0.84 | L3MBTL1 (0.94) | NPSR1L3MBTL1LMNACYP2D6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8647491-B2 | Pyrophosphate-based bath for plating of tin alloy layers | ATOTECH DEUTSCHLAND GMBH (DE) | 2014-02-11 | — | — | US | disclosed |
| US-20100300890-A1 | PYROPHOSPHATE-BASED BATH FOR PLATING OF TIN ALLOY LAYERS | ATOTECH DEUTSCHLAND GMBH (DE) | 2010-12-02 | — | — | US | disclosed |
| EP-2103717-B1 | Pyrophosphate-based bath for depositing tin alloy layers | ATOTECH DEUTSCHLAND GMBH (DE) | 2010-04-21 | — | — | EP | disclosed |
| EP-2103717-A1 | Pyrophosphate-based bath for depositing tin alloy layers | ATOTECH Deutschland GmbH (DE) | 2009-09-23 | — | — | EP | disclosed |
| WO-2009109271-A2 | PYROPHOSPHATE-BASED BATH FOR PLATING ON TIN ALLOY LAYERS | ATOTECH DEUTSCHLAND GMBH (DE) | 2009-09-11 | — | — | WO | disclosed |