Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 1/20 | 0.57 |
| ▸ | PYGL | P06737 | 2/20 | 0.49 |
| ▸ | PLCG2 | P16885 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.46 |
| ▸ | ACP1 | P24666 | 1/20 | 0.46 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.46 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.46 |
| ▸ | SSU72 | Q9NP77 | 1/20 | 0.46 |
| ▸ | PNLIP | P16233 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | PPIA | P62937 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11242701 | 0.92 | PNLIP (0.48) | GCGRPOLBMRGPRX4ACP1PTPN12 | |
| SCHEMBL11237411 | 0.89 | GCGR (0.71) | GCGRPYGLPLCG2NPC1POLB | |
| SCHEMBL11245808 | 0.89 | GCGR (0.64) | GCGRPYGLPLCG2NPC1POLB | |
| SCHEMBL11240584 | 0.88 | PYGL (0.58) | GCGRPYGLPLCG2NPC1POLB | |
| SCHEMBL11228921 | 0.88 | TDP1 (0.56) | GCGRPYGLPLCG2NPC1POLB | |
| SCHEMBL11388824 | 0.85 | GCGR (0.62) | GCGRPYGLNPC1POLBPKM | |
| SCHEMBL11246608 | 0.85 | MRGPRX4 (0.47) | MRGPRX4ACP1PTPN12PTPN13SSU72 | |
| SCHEMBL11246087 | 0.83 | TDP1 (0.70) | GCGRPYGLPLCG2NPC1POLB | |
| SCHEMBL11244138 | 0.80 | GCGR (0.61) | GCGRPYGLPLCG2NPC1POLB | |
| SCHEMBL11251747 | 0.80 | GCGR (0.55) | GCGRPYGLPLCG2NPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4350706-A | MITICIDES, LARVICIDES | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1982-09-21 | — | — | US | disclosed |