Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 5/20 | 0.58 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31329425 | 0.76 | DAO (0.54) | DAOMAOBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3216105 | 0.73 | DAO (1.00) | DAO | |
| SCHEMBL28996301 | 0.70 | RAB9A (0.51) | DAONPC1RAB9ASMN1; SMN2TDP1 | |
| SCHEMBL29128481 | 0.70 | DAO (0.45) | DAOMAOBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1607082 | 0.69 | GAA (0.70) | DAONPC1RAB9ASMN1; SMN2TDP1 | |
| SCHEMBL13504732 | 0.67 | ALDH1A1 (0.53) | DAO | |
| SCHEMBL6815339 | 0.67 | POLB (0.77) | NPC1RAB9ASMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL6829615 | 0.67 | ALDH1A1 (0.50) | DAONPC1RAB9ASMN1; SMN2TDP1 | |
| SCHEMBL24141510 | 0.65 | NPC1 (0.61) | NPC1RAB9ASMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL12442506 | 0.64 | MAPT (0.76) | NPC1RAB9ASMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4332729-A | CATALYZED CYCLIZATION | THE DOW CHEMICAL COMPANY (US) | 1982-06-01 | — | — | US | disclosed |
| US-4331604-A | Preparation of cyclic carbonates | THE DOW CHEMICAL COMPANY (US) | 1982-05-25 | — | — | US | disclosed |