Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.57 |
| ▸ | CDK9 | P50750 | 1/20 | 0.57 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.55 |
| ▸ | NPC1 | O15118 | 4/20 | 0.55 |
| ▸ | RAB9A | P51151 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.52 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | MAOA | P21397 | 2/20 | 0.48 |
| ▸ | MAOB | P27338 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11059549 | 0.96 | SMN1; SMN2 (0.53) | SMN1; SMN2TP53EPHX1TSHREPHX2 | |
| SCHEMBL20938570 | 0.82 | SMN1; SMN2 (0.64) | SMN1; SMN2TP53EPHX1TSHREPHX2 | |
| SCHEMBL14868326 | 0.82 | MAPT (0.44) | SMN1; SMN2TP53EPHX1TSHREPHX2 | |
| SCHEMBL10857203 | 0.82 | MDM2 (0.60) | SMN1; SMN2EPHX1TSHRKMT2ARAB9A | |
| Acetic Acid SCHEMBL27669514 | 0.81 | NAPRT (0.57) | SMN1; SMN2TP53EPHX1TSHREPHX2 | |
| SCHEMBL10857079 | 0.80 | RAB9A (0.57) | TSHRKMT2ANPC1RAB9AMEN1 | |
| SCHEMBL1273883 | 0.80 | MAPT (0.48) | SMN1; SMN2TP53EPHX1TSHREPHX2 | |
| SCHEMBL714237 | 0.80 | SMN1; SMN2 (0.73) | SMN1; SMN2TP53EPHX1TSHREPHX2 | |
| SCHEMBL10401175 | 0.80 | SMN1; SMN2 (0.80) | SMN1; SMN2TP53EPHX1TSHREPHX2 | |
| SCHEMBL4475837 | 0.78 | RAB9A (0.49) | SMN1; SMN2TP53EPHX1TSHREPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4338441-A | CYCLIZATION OF AMIDINOUREA OR AMIDINOTHIOUREA WITH ACTIVE METHYLIDENE COMPOUND | WILLIAM H. RORER, INC. (US) | 1982-07-06 | — | — | US | claimed |