Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.73 |
| ▸ | TP53 | P04637 | 1/20 | 0.73 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.73 |
| ▸ | TSHR | P16473 | 1/20 | 0.73 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.73 |
| ▸ | CDK9 | P50750 | 1/20 | 0.73 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | RECQL | P46063 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.63 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.63 |
| ▸ | NPC1 | O15118 | 3/20 | 0.63 |
| ▸ | RAB9A | P51151 | 3/20 | 0.63 |
| ▸ | CASP3 | P42574 | 1/20 | 0.61 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.60 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.60 |
| ▸ | MAOA | P21397 | 2/20 | 0.59 |
| ▸ | MAOB | P27338 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9479624 | 0.92 | CASP3 (0.77) | SMN1; SMN2TP53EPHX1TSHREPHX2 | |
| SCHEMBL17589369 | 0.90 | KMT2A (0.66) | SMN1; SMN2TP53EPHX1TSHREPHX2 | |
| SCHEMBL20938570 | 0.89 | SMN1; SMN2 (0.64) | SMN1; SMN2TP53EPHX1TSHREPHX2 | |
| SCHEMBL10155599 | 0.87 | ALDH1A1 (0.78) | SMN1; SMN2TP53EPHX1TSHREPHX2 | |
| SCHEMBL8906555 | 0.87 | ALDH1A1 (0.60) | SMN1; SMN2TP53EPHX1TSHREPHX2 | |
| Diphenylurea SCHEMBL133103 | 0.85 | SMN1; SMN2 (1.00) | SMN1; SMN2TP53EPHX1TSHREPHX2 | |
| SCHEMBL23072523 | 0.84 | ALDH1A1 (0.68) | SMN1; SMN2TP53EPHX1TSHREPHX2 | |
| SCHEMBL21504845 | 0.84 | CA1 (0.57) | SMN1; SMN2TP53EPHX1TSHREPHX2 | |
| SCHEMBL21423372 | 0.82 | MAPT (0.69) | SMN1; SMN2TP53EPHX1TSHREPHX2 | |
| SCHEMBL16866541 | 0.82 | ALDH1A1 (0.55) | SMN1; SMN2TP53EPHX1TSHREPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 648 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109563036-A | Novel crystal form of pimavanserin tartrate and preparation method and application thereof | 上海诚妙医药科技有限公司 | 2019-04-02 | — | — | CN | claimed |
| EP-3363788-A1 | CANNABINOID RECEPTOR MODULATORS | Arena Pharmaceuticals, Inc. (US) | 2018-08-22 | — | — | EP | claimed |
| CN-107848972-A | For preparing N (4 luorobenzyl) N (base of 1 methyl piperidine 4) N ' (4 (2 methyl propoxyl group) phenyl methyl) ureas and its tartrate and polymorphic C method | 阿卡蒂亚药品公司 | 2018-03-27 | — | — | CN | claimed |
| EP-2991970-A1 | PART-STREAM DISTILLATION | BASF SE (DE) | 2016-03-09 | — | — | EP | claimed |
| WO-2014177507-A1 | PART-STREAM DISTILLATION | BASF SE (DE) | 2014-11-06 | — | — | WO | claimed |
| EP-1971600-B1 | ISOXAZOLE DERIVATIVES AND USE THEREOF | SK BIOPHARMACEUTICALS CO LTD (KR) | 2013-08-21 | — | — | EP | claimed |
| US-20130165412-A1 | CANNABINOID RECEPTOR MODULATORS | ARENA PHARMACEUTICALS, INC. | 2013-06-27 | — | — | US | claimed |
| US-20120214766-A1 | CANNABINOID RECEPTOR MODULATORS | ARENA PHARMACEUTICALS, INC. | 2012-08-23 | — | — | US | claimed |
| EP-2470508-A1 | CANNABINOID RECEPTOR MODULATORS | Arena Pharmaceuticals, Inc. (US) | 2012-07-04 | — | — | EP | claimed |
| WO-2011025541-A1 | CANNABINOID RECEPTOR MODULATORS | ARENA PHARMACEUTICALS, INC. (US) | 2011-03-03 | — | — | WO | claimed |
| EP-0017706-B1 | N'-PHENYL-N-METHYLUREA DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THEIR USES AS HERBICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1983-08-03 | — | — | EP | claimed |
| EP-0040859-B1 | N'-PHENYL-N-METHYLUREA DERIVATIVES, THEIR PRODUCTION AND USE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1983-08-03 | — | — | EP | claimed |
| US-4384999-A | Preparation of alkyl isocyanates | SPAZIANTE PLACIDO M | 1983-05-24 | — | — | US | claimed |
| EP-0075434-A2 | Cephalosporins, their preparation and their pharmaceutical compositions | ICI PHARMA (FR) | 1983-03-30 | — | — | EP | claimed |
| EP-0072608-A2 | Process for the preparation of cephalosporin derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1983-02-23 | — | — | EP | claimed |
| EP-0071370-A2 | Cephalosporin derivatives, process for their preparation and pharmaceutical compositions containing them | ICI PHARMA (FR) | 1983-02-09 | — | — | EP | claimed |
| EP-0055562-A2 | Cephalosporin derivatives | ICI PHARMA (FR) | 1982-07-07 | — | — | EP | claimed |
| EP-0055099-A1 | Penicillin derivatives | ICI PHARMA (FR) | 1982-06-30 | — | — | EP | claimed |
| EP-0040859-A1 | N'-phenyl-N-methylurea derivatives, their production and use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1981-12-02 | — | — | EP | claimed |
| EP-0017706-A2 | N'-Phenyl-N-methylurea derivatives, processes for their preparation and their uses as herbicides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1980-10-29 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120214766-A1 | CANNABINOID RECEPTOR MODULATORS | CNR1, CNR2, TRPV1 | SMN1; SMN2 208/4885TP53 2675/4885EPHX1 2616/4885 |
| US-20130165412-A1 | CANNABINOID RECEPTOR MODULATORS | CNR1, CNR2, TRPV1 | SMN1; SMN2 208/4885TP53 2675/4885EPHX1 2616/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.