Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.38 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.38 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 5/20 | 0.36 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10860882 | 0.85 | TSHR (0.46) | TXNRD1TXNRD3TXNRD2TSHRGPR35 | |
| SCHEMBL6835578 | 0.78 | TXNRD1 (0.39) | TXNRD1TXNRD3TXNRD2TSHRGPR35 | |
| SCHEMBL1132751 | 0.77 | TXNRD1 (0.41) | TXNRD1TXNRD3TXNRD2TSHRGPR35 | |
| SCHEMBL2831050 | 0.76 | TXNRD1 (0.46) | TXNRD1TXNRD3TXNRD2TSHRGPR35 | |
| SCHEMBL9260 | 0.76 | ALDH1A1 (0.55) | TSHRTDP1ALDH1A1HPGDHTT | |
| SCHEMBL95713 | 0.75 | CYP1A2 (0.54) | TXNRD1TXNRD3TXNRD2TSHRGPR35 | |
| SCHEMBL1828132 | 0.74 | TSHR (0.47) | TXNRD1TXNRD3TXNRD2TSHRGPR35 | |
| SCHEMBL95261 | 0.74 | VCAM1 (0.47) | TSHRTDP1ALDH1A1HPGDNPC1 | |
| SCHEMBL25770 | 0.74 | ALDH1A1 (0.41) | TSHRTDP1ALDH1A1HTTCYP1A2 | |
| SCHEMBL6038159 | 0.73 | TXNRD1 (0.56) | TXNRD1TXNRD3TXNRD2TDP1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4314936-A | BY MEASUREM,ENT OF FLUORESENCE | YEDA RESEARCH AND DEVELOPMENT CO., LTD. (IL) | 1982-02-09 | — | — | US | claimed |
| US-4314936-A | BY MEASUREM,ENT OF FLUORESENCE | YEDA RESEARCH AND DEVELOPMENT CO., LTD. (IL) | 1982-02-09 | — | — | US | disclosed |