Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 3/20 | 0.46 |
| ▸ | ESR1 | P03372 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | LTA4H | P09960 | 3/20 | 0.43 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.42 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | BAX | Q07812 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17911615 | 0.87 | ALDH1A3 (0.41) | KMT2ACA12CA1CA2CA9 | |
| SCHEMBL1477040 | 0.80 | ESR2 (0.50) | ESR2ESR1KMT2AMEN1LTA4H | |
| SCHEMBL28485 | 0.80 | KMT2A (0.56) | ESR2ESR1KMT2AMEN1LTA4H | |
| SCHEMBL16902830 | 0.80 | ESR2 (0.50) | ESR2ESR1KMT2AMEN1LTA4H | |
| SCHEMBL16800113 | 0.79 | KMT2A (0.45) | ESR1KMT2AMEN1LMNAMAPT | |
| SCHEMBL4074898 | 0.78 | ACHE (0.46) | KMT2AMEN1LMNACYP3A4MAPT | |
| SCHEMBL28835255 | 0.78 | CA1 (0.55) | LTA4HCYP3A4MAPTCA12CA1 | |
| SCHEMBL4163652 | 0.78 | LDHA (0.48) | KMT2AMEN1LMNAMAPTCA1 | |
| SCHEMBL6061597 | 0.78 | ESR2 (0.48) | ESR2ESR1KMT2AMEN1LTA4H | |
| SCHEMBL8418539 | 0.76 | ESR2 (0.48) | ESR2ESR1KMT2AMEN1LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4310527-A | DISORDERS OF CAROIAC RHYTHM AND CORONARY HEART DISEASES AND HYDPERTENSION | CIBA-GEIGY CORPORATION (US) | 1982-01-12 | — | — | US | disclosed |