Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 12/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.40 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10356810 | 0.81 | ALDH1A1 (0.36) | CHRM1CHRM3MAOA | |
| SCHEMBL6266552 | 0.79 | SIGMAR1 (0.49) | OPRM1SIGMAR1SLC22A1NR1I2ABCB1 | |
| SCHEMBL28275930 | 0.71 | OPRM1 (0.38) | OPRM1SIGMAR1SLC22A1NR1I2ABCB1 | |
| SCHEMBL3285069 | 0.67 | ALDH1A1 (0.50) | OPRM1SIGMAR1 | |
| SCHEMBL8619637 | 0.65 | ALDH1A1 (0.52) | OPRM1SIGMAR1 | |
| SCHEMBL2781437 | 0.65 | ALDH1A1 (0.63) | OPRM1SIGMAR1 | |
| SCHEMBL8544469 | 0.64 | ALDH1A1 (0.45) | — | |
| Hydrochloric Acid SCHEMBL11688433 | 0.64 | ALDH1A1 (0.47) | OPRM1SIGMAR1 | |
| SCHEMBL2639776 | 0.64 | ALDH1A1 (0.46) | OPRM1SIGMAR1SLC22A1CHRM1CHRM3 | |
| SCHEMBL28741426 | 0.64 | SIGMAR1 (0.41) | OPRM1SIGMAR1SLC22A1NR1I2ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4338445-A | N-(Carbonylamino)-tetrahydropyridyl derivatives | CANADIAN PATENTS & DEVELOPMENT LIMITED (CA) | 1982-07-06 | — | — | US | claimed |