Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.38 |
| ▸ | SCN4A | P35499 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | CASR | P41180 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11235606 | 0.99 | LMNA (0.38) | LMNAMEN1KMT2AOPRM1OPRD1 | |
| SCHEMBL11242824 | 0.90 | TRPV4 (0.44) | LMNAMEN1KMT2AOPRM1OPRD1 | |
| SCHEMBL11231201 | 0.87 | NPC1 (0.43) | LMNAMEN1KMT2AOPRM1OPRD1 | |
| Hydrochloric Acid SCHEMBL11226919 | 0.86 | ADRB2 (0.42) | LMNAMEN1KMT2AOPRM1OPRD1 | |
| SCHEMBL11244731 | 0.85 | TSHR (0.43) | LMNAMEN1KMT2AOPRM1OPRD1 | |
| SCHEMBL11229502 | 0.84 | THRB (0.46) | LMNAMEN1KMT2ATRPV4MAPT | |
| Hydrochloric Acid SCHEMBL11237741 | 0.84 | TSHR (0.43) | LMNAMEN1KMT2AOPRM1OPRD1 | |
| Hydrochloric Acid SCHEMBL11238434 | 0.83 | THRB (0.46) | LMNAMEN1KMT2ATRPV4MAPT | |
| SCHEMBL11237785 | 0.82 | SCN4A (0.46) | LMNAMEN1KMT2AOPRM1OPRD1 | |
| SCHEMBL11238354 | 0.81 | TRPV4 (0.48) | LMNAMEN1KMT2ATRPV4SCN4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4356322-A | ADRENERGIC STIMULANTS; CARDIOTONIC AGENTS | VEB ARZNEIMITTELWERK DRESDEN (DD) | 1982-10-26 | — | — | US | claimed |