Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | BCL9 | O00512 | 1/20 | 0.55 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14032363 | 0.87 | ALDH1A1 (0.68) | ALDH1A1BCL9CTNNB1CYP2C19CYP1A2 | |
| SCHEMBL12179295 | 0.86 | CYP2C19 (0.54) | ALDH1A1CYP2C19CYP1A2MAPTGAA | |
| SCHEMBL6932662 | 0.85 | CYP2C19 (0.61) | ALDH1A1CYP2C19CYP1A2MAPTGAA | |
| SCHEMBL11239432 | 0.85 | TSHR (0.56) | ALDH1A1BCL9CTNNB1CYP2C19MAPT | |
| SCHEMBL6647402 | 0.84 | TSHR (0.59) | ALDH1A1CYP2C19CYP1A2MAPTGAA | |
| SCHEMBL5496017 | 0.83 | CYP2C19 (0.55) | ALDH1A1CYP2C19CYP1A2MAPTGAA | |
| SCHEMBL24221950 | 0.81 | L3MBTL1 (0.65) | ALDH1A1CYP2C19CYP1A2MAPTTSHR | |
| SCHEMBL6808768 | 0.80 | TSHR (0.58) | ALDH1A1CYP2C19CYP1A2MAPTGAA | |
| SCHEMBL11373145 | 0.79 | CYP2C19 (0.54) | ALDH1A1CYP2C19CYP1A2MAPTGAA | |
| SCHEMBL22408746 | 0.79 | CYP2C19 (0.54) | ALDH1A1CYP2C19CYP1A2MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996030350-A1 | AMIDINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-10-03 | — | — | WO | disclosed |