Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | ACE | P12821 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.31 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11239659 | 1.00 | ALDH1A1 (0.36) | ALDH1A1HPGDSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL11239164 | 0.90 | SMN1; SMN2 (0.39) | ALDH1A1HPGDSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL11239169 | 0.90 | SMN1; SMN2 (0.39) | ALDH1A1HPGDSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL27160438 | 0.79 | RORC (0.46) | MAPK1 | |
| SCHEMBL27160443 | 0.79 | RORC (0.46) | MAPK1 | |
| SCHEMBL7036716 | 0.78 | SMN1; SMN2 (0.44) | ALDH1A1HPGDSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL11240063 | 0.77 | NPC1 (0.35) | ALDH1A1SMN1; SMN2RAB9ANPC1MAPT | |
| SCHEMBL11240057 | 0.77 | NPC1 (0.35) | ALDH1A1SMN1; SMN2RAB9ANPC1MAPT | |
| SCHEMBL11234753 | 0.71 | CHRM2 (0.31) | ALDH1A1CHRM1CHRM4 | |
| SCHEMBL7335086 | 0.71 | OPRM1 (0.44) | ALDH1A1KMT2AACEMEN1CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4320137-A | Derivatives of perhydro-aza-heterocycles | CIBA-GEIGY CORPORATION (US) | 1982-03-16 | — | — | US | disclosed |
| US-4246269-A | Antidepressant piperidinones | CIBA-GEIGY CORPORATION (US) | 1981-01-20 | — | — | US | disclosed |
| US-4160837-A | ANTIDEPRESSANTS | CIBA-GEIGY CORPORATION (US) | 1979-07-10 | — | — | US | disclosed |