Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT1 | P35610 | 3/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.31 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11247610 | 0.88 | SOAT1 (0.39) | SOAT1 | |
| SCHEMBL11242387 | 0.85 | SLC6A3 (0.34) | SOAT1 | |
| SCHEMBL11243234 | 0.84 | SOAT1 (0.33) | SOAT1 | |
| SCHEMBL11236878 | 0.80 | SOAT1 (0.37) | SOAT1 | |
| SCHEMBL11238469 | 0.80 | POLB (0.33) | SOAT1 | |
| SCHEMBL11246601 | 0.79 | SOAT1 (0.39) | SOAT1GRIN1GRIN2A | |
| SCHEMBL11240566 | 0.78 | GRIN1 (0.41) | GRIN1GRIN2A | |
| SCHEMBL9795583 | 0.76 | ALDH1A1 (0.49) | SOAT1 | |
| SCHEMBL11234440 | 0.75 | MEN1 (0.39) | SOAT1 | |
| SCHEMBL11256266 | 0.74 | SLC6A2 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0049565-A2 | Derivatives of substituted N-alkylimidazoles, their preparation and pharmaceutical compositions containing them | SYNTEX (U.S.A.) INC. (US) | 1982-04-14 | — | — | EP | disclosed |
| US-4321272-A | Derivatives of substituted N-alkylimidazoles | SYNTEX (U.S.A.) INC. (US) | 1982-03-23 | — | — | US | disclosed |